MLS003124364 (CID 46948235) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(6)
 
 
Inactive(137)
 
 
Inconclusive(6)
 
 
Top Targets:
7TM GPCR Srx(8)
 
 
 
7TM GPCR Srsx(4)
 
 
rad52(2)
 
 
Peptidase M27(2)
 
 
PRK00058(2)
 
 
BioAssay Types:
Screening(114)
 
 
 
 
Confirmatory(29)
 
 
 
 
Literature(3)
 
 
BioActivity Types:
Potency(24)
 
 
 
 
AC50(5)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 149    Data Row: 149   Total Pages: 3   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID99494853]
AC50 3.43FRET-based HTS for detection of RAD52 Inhibitors Measured in Biochemical System Using Plate Reader - 7018-01_Inhibitor_Dose_CherryPick_Activity [AID652116, Type: confirmatory]RAD52 gene product [Homo sapiens] [gi:109637798]
View
2
[SID99494853]
Potency 20.5962qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
View
3
[SID99494853]
AC50 22.25Identification of Inhibitors of RAD54 Measured in Biochemical System Using Plate Reader - 2159-01_Inhibitor_Dose_CherryPick_Activity [AID651657, Type: confirmatory]RAD54L gene product [Homo sapiens] [gi:216548193]
View
4
[SID99494853]
Potency 23.1093qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
View
5
[SID99494853]
Potency 23.1093qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
View
6
[SID99494853]
Potency 23.1093qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
View
7
[SID99494853]
 FRET-based HTS for detection of RAD52 Inhibitors Measured in Biochemical System Using Plate Reader - 7018-01_Inhibitor_SinglePoint_HTS_Activity_Set2 [AID651710, Type: screening]RAD52 gene product [Homo sapiens] [gi:109637798]
View
8
[SID99494853]
 Identification of inhibitors of RAD54 Measured in Biochemical System Using Plate Reader - 2159-01_Inhibitor_SinglePoint_HTS_Activity [AID602329, Type: screening]RAD54L gene product [Homo sapiens] [gi:216548193]
View
9
[SID99494853]
Potency 11.2202qHTS for Inhibitors of TGF-b: Cytotox Counterscreen [AID588856, Type: confirmatory]
View
10
[SID99494853]
 uHTS luminescent assay for identification of compounds that enhance the survival of human induced pluripotent stem cells when cultured as single cells [AID602274, Type: screening]
View
11
[SID99494853]
 HTS for suppressors of simvastatin-induced mytoxicity in differentiated C2C12 cells Measured in Cell-Based System Using Plate Reader - 2112-01_Suppressor_SinglePoint_HTS_Activity [AID602340, Type: screening]
View
12
[SID99494853]
 Whole cell Yeast HTS to identify compounds modulating the fidelity of the start codon recognition in eukaryotes. Measured in Whole Organism System Using Plate Reader - 2155-01_Other_SinglePoint_HTS_Activity [AID602363, Type: screening]
View
13
[SID99494853]
 Schnurri-3 Inhibitors: specific inducers of adult bone formation Measured in Cell-Based System Using Plate Reader - 2134-01_Inhibitor_SinglePoint_HTS_Activity_Set2 [AID588674, Type: screening]
View
14
[SID99494853]
 uHTS identification of small molecule inhibitors of the mitochondrial permeability transition pore via an absorbance assay [AID602449, Type: screening]
View
15
[SID99494853]
 HTS to identify compounds that promote myeloid differentiation with MLPCN compound set [AID624256, Type: screening]
View
16
[SID99494853]
Potency qHTS of GLP-1 Receptor Inverse Agonists: Cytotox Screen [AID624418, Type: confirmatory]
View
17
[SID99494853]
 Counterscreen of compound fluorescence effects on High-throughput multiplex microsphere screening for inhibitors of toxin protease [AID624483, Type: screening]
View
18
[SID99494853]
 uHTS identification of small molecule Triacylglycerol inhbitors in a fluoresence assay [AID651582, Type: screening]
View
19
[SID99494853]
 HIV entry: Env-mediated Cell Fusion Measured in Cell-Based System Using Plate Reader - 7013-01_Inhibitor_SinglePoint_HTS_Activity [AID651610, Type: screening]
View
20
[SID99494853]
 DENV2 CPE-Based HTS Measured in Cell-Based and Microorganism Combination System Using Plate Reader - 2149-01_Other_SinglePoint_HTS_Activity [AID651640, Type: screening]
View
21
[SID99494853]
 Luminescence Cell-Based Primary HTS to identify inhibitors of the oncoprotein EWS/Fli transcriptional activity Measured in Cell-Based System Using Plate Reader - 7014-01_Inhibitor_SinglePoint_HTS_Activity [AID651661, Type: screening]
View
22
[SID99494853]
AC50 Identification of Rad54 Inhibitors - Ruling Out Compounds That Bind DNA Measured in Biochemical System Using Plate Reader - 2159-04_Inhibitor_Dose_CherryPick_Activity [AID651673, Type: confirmatory]
View
23
[SID99494853]
AC50 Cytotoxicity assay Measured in Cell-Based System Using Plate Reader - 2159-05_Inhibitor_Dose_CherryPick_Activity [AID651692, Type: confirmatory]
View
24
[SID99494853]
 HTS for the detection of C. neoformans cell lysis via adenylate kinase (AK) release Measured in Microorganism System Using Plate Reader - 2162-01_Inhibitor_SinglePoint_HTS_Activity [AID651654, Type: screening]
View
25
[SID99494853]
 Fluorescence-based biochemical primary high throughput screening assay to identify molecules that bind r(CAG) RNA repeats [AID651821, Type: screening]
View
26
[SID99494853]
 Flow Cytometric HTS Screening for Inhibitors of Lytic Granule Exocytosis with MLPCN Compound Library [AID651702, Type: screening]
View
27
[SID99494853]
AC50 RAD52: DNA binders Measured in Biochemical System Using Plate Reader - 7018-02_Inhibitor_Dose_CherryPick_Activity [AID652128, Type: confirmatory]
View
28
[SID99494853]
 qHTS of D3 Dopamine Receptor Agonist: qHTS [AID652048, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
View
29
[SID99494853]
 qHTS of D3 Dopamine Receptor Agonist: qHTS [AID652048, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
View
30
[SID99494853]
 qHTS of D3 Dopamine Receptor Agonist: qHTS [AID652048, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
View
31
[SID99494853]
 qHTS of D3 Dopamine Receptor Agonist: qHTS [AID652048, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
View
32
[SID99494853]
 qHTS of D3 Dopamine Receptor Antagonist: qHTS [AID652054, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
View
33
[SID99494853]
 qHTS of D3 Dopamine Receptor Antagonist: qHTS [AID652054, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
View
34
[SID99494853]
 qHTS of D3 Dopamine Receptor Antagonist: qHTS [AID652054, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
View
35
[SID99494853]
 qHTS of D3 Dopamine Receptor Antagonist: qHTS [AID652054, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
View
36
[SID99494853]
 qHTS of D3 Dopamine Receptor Potentiators: qHTS [AID652051, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
View
37
[SID99494853]
 qHTS of D3 Dopamine Receptor Potentiators: qHTS [AID652051, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
View
38
[SID99494853]
 qHTS of D3 Dopamine Receptor Potentiators: qHTS [AID652051, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
View
39
[SID99494853]
 qHTS of D3 Dopamine Receptor Potentiators: qHTS [AID652051, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
View
40
[SID99494853]
 uHTS identification of small molecule antagonists of the EBI2 receptor via a luminescent beta-arrestin assay [AID651636, Type: screening]GPR183 gene product [Homo sapiens] [gi:4826706]
View
41
[SID99494853]
 uHTS identification of HIF-2a Inhibitors in a luminesence assay [AID624352, Type: screening]EPAS1 gene product [Homo sapiens] [gi:40254439]
View
42
[SID99494853]
 uHTS identification of HIF-2a Inhibitors in a luminesence assay [AID624352, Type: screening]EPAS1 gene product [Homo sapiens] [gi:40254439]
View
43
[SID99494853]
 uHTS identification of small molecule inhibitors of the thioesterase domain of fatty acid synthase via a fluorescence intensity assay [AID602261, Type: screening]FASN gene product [Homo sapiens] [gi:41872631]
View
44
[SID99494853]
 uHTS identification of small molecule inhibitors of the thioesterase domain of fatty acid synthase via a fluorescence intensity assay [AID602261, Type: screening]FASN gene product [Homo sapiens] [gi:41872631]
View
45
[SID99494853]
 uHTS identification of small molecule inhibitors of the thioesterase domain of fatty acid synthase via a fluorescence intensity assay [AID602261, Type: screening]FASN gene product [Homo sapiens] [gi:41872631]
View
46
[SID99494853]
 Luminescence-based cell-based primary high throughput screening assay to identify inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID602396, Type: screening]NR5A2 gene product [Homo sapiens] [gi:4504343]
View
47
[SID99494853]
 Luminescence-based cell-based primary high throughput screening assay to identify inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID602396, Type: screening]NR5A2 gene product [Homo sapiens] [gi:4504343]
View
48
[SID99494853]
Potency qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode) [AID624417, Type: confirmatory]glp-1 receptor [Homo sapiens] [gi:1724069]
View
49
[SID99494853]
Potency qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode) [AID624417, Type: confirmatory]glp-1 receptor [Homo sapiens] [gi:1724069]
View
50
[SID99494853]
Potency qHTS of GLP-1 Receptor Agonists [AID624172, Type: confirmatory]glp-1 receptor [Homo sapiens] [gi:1724069]
View