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AC1NFZUA (CID 4691858) - Compound BioActivity Data
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BioActivity Outcomes:
Active(44)
 
 
Inactive(633)
 
 
Inconclusive(31)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(44)
 
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
Tryp SPc(8)
 
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(469)
 
 
 
 
Confirmatory(215)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(150)
 
 
 
 
 
IC50(41)
 
 
 
 
EC50(10)
 
 
 
AC50(8)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 642    Data Row: 709   Total Pages: 36   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17514194]
AC50_uM 2.092Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Cancer Stem Cells [AID449748, Type: confirmatory]
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2
[SID17514194]
AC50_uM 4.499Dose Response HTS Screen to Identify Cytotoxic Compounds of HMLE_sh_eGFP [AID463074, Type: confirmatory]
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3
[SID17514194]
AC50_uM 7.509Fluorescence Cell-Free Homogeneous Secondary Screen to Identify Inhibitors of DnaB-Intein Splicing Activity [AID449749, Type: confirmatory]replicative DNA helicase [Mycobacterium tuberculosis H37Rv] [gi:15607200]
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4
[SID17514194]
IC50 7.724Counterscreen for exosite inhibitors of ADAM17: Fluorescence resonance energy transfer (FRET)-based biochemical high throughput dose response assay to identify inhibitors of ADAM10 [AID743259, Type: confirmatory]ADAM10 [Homo sapiens] [gi:2393947]
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5
[SID17514194]
AC50_uM 7.733Trypsin Inhibition Assay Measured in Biochemical System Using Plate Reader - 2034-02_Inhibitor_Dose_CherryPick_Activity [AID488789, Type: confirmatory]Trypsin [gi:136429]
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6
[SID17514194]
Potency 9.2qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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7
[SID17514194]
Potency 10.4179Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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8
[SID17514194]
Potency 11.5821qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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9
[SID17514194]
Potency 12.5893qHTS for Inhibitors of ATXN expression [AID651635, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
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10
[SID17514194]
Potency 12.9953qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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11
[SID17514194]
AC50_uM 13.09Fluorescence Cell-Free Homogeneous Secondary Screen to Identify Non-Covalent Inhibitors of RecA-Intein Splicing Activity [AID449750, Type: confirmatory]replicative DNA helicase [Mycobacterium tuberculosis H37Rv] [gi:15607200]
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12
[SID17514194]
Potency 14.581qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1 [AID504467, Type: confirmatory]ATAD5 protein, partial [Homo sapiens] [gi:116283940]
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13
[SID17514194]
Potency 16.3601qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
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14
[SID17514194]
Potency 16.3601A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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15
[SID17514194]
EC50_uM 16.7Fluorescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of RecA-Intein Splicing Activity [AID435010, Type: confirmatory]recombinase A [Mycobacterium tuberculosis H37Rv] [gi:15609874]
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16
[SID17514194]
Potency 22.3872qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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17
[SID17514194]
Potency 23.1093qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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18
[SID17514194]
AC50_uM 27.2Ras-converting Enzyme/Cell Proliferation Pathway Measured in Biochemical System Using Plate Reader - 2034-01_Inhibitor_Dose_CherryPick [AID488788, Type: confirmatory]Rce1p [Saccharomyces cerevisiae S288c] [gi:6323930]
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19
[SID17514194]
EC50_uM 32.83Fluorescence Cell-Free Homogeneous Counter Screen to Identify Inhibitors of GFP Chromophore Formation [AID434968, Type: confirmatory]recombinase A [Mycobacterium tuberculosis H37Rv] [gi:15609874]
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20
[SID17514194]
Potency 44.6684qHTS Assay for Inhibitors of BAZ2B [AID504333, Type: confirmatory]bromodomain adjacent to zinc finger domain 2B [Homo sapiens] [gi:6683500]
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