CHEMBL1171494
(CID
46913222
) -
BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(
1
)
Top Targets:
p450(
1
)
BioAssay Types:
Literature(
1
)
BioActivity Types:
IC50(
1
)
SAR
Target summary
Data download
Chemical Probe
Active
Inactive
Inconclusive
Unspecified
Total Bioassays: 1 Data Row: 1 Total Pages: 1
#
Substance
Activity
BioAssay
Target
Links
Outcome
Type
Value [μM]
1
[SID
103768403
]
Active
IC50
0.3
Inhibition of human recombinant CYP24A1 expressed in chinese hamster V79 cells using [3H-1-beta]calcitriol after 60 mins by scintillation counting [AID
492342
, Type: Literature]
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial [gi:
19862747
]
View
X
Row No.
1
Structure
Substance
SID
103768403
CID
46913222
Outcome
Active
IC50
0.3 [uM]
BioAssay
Inhibition of human recombinant CYP24A1 expressed in chinese hamster V79 cells using [3H-1-beta]calcitriol after 60 mins by scintillation counting
AID
492342
BioAssay type
Literature
Target
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial [gi:
19862747
]
PubMed
20594862
Data Table
Chemical Probe 
Active 
Inactive 
Inconclusive 
Unspecified 
