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CHEMBL1726915 (CID 46907733) - Compound BioActivity Data
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BioActivity Outcomes:
Active(5)
 
 
Inactive(1)
 
 
Inconclusive(2)
 
 
Unspecified(2)
 
 
Top Targets:
Firefly Luc l..(2)
 
 
TUDOR(2)
 
 
WW(1)
 
 
BioAssay Types:
Literature(6)
 
 
 
 
Confirmatory(4)
 
 
 
BioActivity Types:
Potency(4)
 
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 10    Data Row: 10   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID99367986]
Potency 0.0688Confirmation Concentration-Response Assay for Enhancers of SMN2 Splice Variant Expression for Further Probe SAR [AID488832, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
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2
[SID99367986]
Potency 2.4424Counterscreen Assay for Enhancers of SMN2 Splice Variant Expression: Modulation of SMN1 Expression for Further Probe SAR [AID488821, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:4507091]
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3
[SID99367986]
Potency 5.0456Counterscreen Assay for Enhancers of SMN2 Splice Variant Expression: Interaction with Luciferase Reporter for Further Probe SAR [AID488838, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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4
[SID134453378]
IC50 6.4Inhibition of fire fly luciferase [AID616340, Type: Literature]Luciferin 4-monooxygenase [gi:266484]
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5
[SID134453378]
Activation of SMN expressed in HEK293 cells assessed as concentration required to reach 50% of maximum luciferase signal by SMN2-promotor driven luciferase reporter gene assay [AID616344, Type: Literature]
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6
[SID134453378]
Half-life in mouse liver microsome at 1 uM [AID616339, Type: Literature]
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7
[SID134453378]
Activation of SMN expressed in HEK293 cells assessed as rate of induction by SMN2-promotor driven luciferase reporter gene assay relative to basal level [AID616343, Type: Literature]
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8
[SID99367986]
Potency qHTS Assay to Find Inhibitors of Pin1 [AID504891, Type: confirmatory]peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [Homo sapiens] [gi:5453898]
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9
[SID134453378]
Apparent permeability from basolateral side to apical side of human Caco2 cells at 10 uM [AID616337, Type: Literature]
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10
[SID134453378]
Apparent permeability from apical side to basolateral side of human Caco2 cells at 10 uM [AID616338, Type: Literature]
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