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AGN-PC-080QYT (CID 46907716) - Compound BioActivity Data
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BioActivity Outcomes:
Active(4)
 
 
Inactive(4)
 
 
Inconclusive(3)
 
 
Unspecified(1)
 
 
Top Targets:
TUDOR(2)
 
 
 
Firefly Luc l..(2)
 
 
TCP1 beta(1)
 
 
Ape1-like AP-..(1)
 
 
BioAssay Types:
Confirmatory(8)
 
 
 
 
Literature(4)
 
 
 
 
BioActivity Types:
Potency(8)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 12    Data Row: 12   Total Pages: 1   
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID99367908]
Potency 1.091Confirmation Concentration-Response Assay for Enhancers of SMN2 Splice Variant Expression for Further Probe SAR [AID488832, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
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2
[SID99367908]
Potency 16.9441qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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3
[SID99367908]
Potency 25.2879Counterscreen Assay for Enhancers of SMN2 Splice Variant Expression: Interaction with Luciferase Reporter for Further Probe SAR [AID488838, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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4
[SID134453379]
Activation of SMN expressed in HEK293 cells assessed as concentration required to reach 50% of maximum luciferase signal by SMN2-promotor driven luciferase reporter gene assay [AID616344, Type: Literature]
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5
[SID134453379]
Activation of SMN expressed in HEK293 cells assessed as rate of induction by SMN2-promotor driven luciferase reporter gene assay relative to basal level [AID616343, Type: Literature]
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6
[SID99367908]
Potency qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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7
[SID99367908]
Potency Inhibitors of TCP-1 ring complex (TRiC) of Methanococcus maripaludis (MmCpn): qHTS [AID504842, Type: confirmatory]chaperonin-containing TCP-1 beta subunit homolog [Homo sapiens] [gi:4090929]
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8
[SID99367908]
Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign [AID504810, Type: Literature]TSHR protein [Homo sapiens] [gi:118341367]
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9
[SID99367908]
Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign [AID504812, Type: Literature]TSHR protein [Homo sapiens] [gi:118341367]
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10
[SID99367908]
Potency 2.9362Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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11
[SID99367908]
Potency 11.6891Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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12
[SID99367908]
Potency 38.7098Counterscreen Assay for Enhancers of SMN2 Splice Variant Expression: Modulation of SMN1 Expression for Further Probe SAR [AID488821, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:4507091]
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