Bookmark and Share
CHEMBL1719232 (CID 46907708) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(15)
 
 
Inactive(1)
 
 
Unspecified(23)
 
 
Top Targets:
TUDOR(2)
 
 
Firefly Luc l..(2)
 
 
WW(1)
 
 
BioAssay Types:
Literature(35)
 
 
 
Confirmatory(4)
 
 
 
BioActivity Types:
Potency(4)
 
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 39    Data Row: 39   Total Pages: 2   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID99367988]
Potency 0.0688Confirmation Concentration-Response Assay for Enhancers of SMN2 Splice Variant Expression for Further Probe SAR [AID488832, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
View
2
[SID99367988]
Potency 0.7997Counterscreen Assay for Enhancers of SMN2 Splice Variant Expression: Interaction with Luciferase Reporter for Further Probe SAR [AID488838, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
3
[SID134457200]
IC50 0.8Inhibition of fire fly luciferase [AID616340, Type: Literature]Luciferin 4-monooxygenase [gi:266484]
View
4
[SID99367988]
Potency 4.8733Counterscreen Assay for Enhancers of SMN2 Splice Variant Expression: Modulation of SMN1 Expression for Further Probe SAR [AID488821, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:4507091]
View
5
[SID134457200]
Activation of SMN expressed in HEK293 cells assessed as concentration required to reach 50% of maximum luciferase signal by SMN2-promotor driven luciferase reporter gene assay [AID616344, Type: Literature]
View
6
[SID134457200]
Plasma concentration in Swiss albino mouse at 30 mg/kg, po after 24 hrs [AID616328, Type: Literature]
View
7
[SID134457200]
Plasma concentration in Swiss albino mouse at 30 mg/kg, po after 12 hrs [AID616329, Type: Literature]
View
8
[SID134457200]
Plasma concentration in Swiss albino mouse at 30 mg/kg, po after 8 hrs [AID616330, Type: Literature]
View
9
[SID134457200]
Plasma concentration in Swiss albino mouse at 30 mg/kg, po after 4 hrs [AID616331, Type: Literature]
View
10
[SID134457200]
Plasma concentration in Swiss albino mouse at 30 mg/kg, po after 2 hrs [AID616332, Type: Literature]
View
11
[SID134457200]
Plasma concentration in Swiss albino mouse at 30 mg/kg, po after 1 hr [AID616333, Type: Literature]
View
12
[SID134457200]
Plasma concentration in Swiss albino mouse at 30 mg/kg, po after 0.5 hrs [AID616334, Type: Literature]
View
13
[SID134457200]
Plasma concentration in Swiss albino mouse at 30 mg/kg, po after 0.25 hrs [AID616335, Type: Literature]
View
14
[SID134457200]
Plasma concentration in Swiss albino mouse at 30 mg/kg, po after 0.083 hrs [AID616336, Type: Literature]
View
15
[SID134457200]
Cmax in plasma of Swiss albino mouse at 30 mg/kg, po [AID616274, Type: Literature]
View
16
[SID134457200]
Tmax in plasma of Swiss albino mouse at 30 mg/kg, po [AID616275, Type: Literature]
View
17
[SID134457200]
Drug level in Swiss albino mouse brain at 30 mg/kg, po after 24 hrs [AID616276, Type: Literature]
View
18
[SID134457200]
Drug level in Swiss albino mouse brain at 30 mg/kg, po after 12 hrs [AID616277, Type: Literature]
View
19
[SID134457200]
Drug level in Swiss albino mouse brain at 30 mg/kg, po after 8 hrs [AID616278, Type: Literature]
View
20
[SID134457200]
Drug level in Swiss albino mouse brain at 30 mg/kg, po after 4 hrs [AID616279, Type: Literature]
View