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MLS003151719 (CID 46904985) - Compound BioActivity Data
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BioActivity Outcomes:
Active(5)
 
 
Inactive(220)
 
 
Inconclusive(1)
 
 
Top Targets:
7TM GPCR Srsx(10)
 
 
7TM GPCR Srx(7)
 
 
CAP ED(4)
 
 
RasGEF(4)
 
 
Anthrax-tox M(3)
 
 
BioAssay Types:
Screening(166)
 
 
 
Confirmatory(48)
 
 
 
 
Literature(9)
 
 
BioActivity Types:
Potency(43)
 
 
 
 
IC50(5)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 208    Data Row: 226   Total Pages: 12   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID99361135]
IC50_Mean 8.84Dose response confirmation of uHTS inhibitor hits of the mitochondrial permeability transition pore via an absorbance assay [AID651561, Type: confirmatory]
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2
[SID99361135]
Potency 11.5821qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID99361135]
Potency 14.581qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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4
[SID99361135]
IC50_Mean 29.1Dose response confirmation of uHTS inhibitor hits of the mitochondrial permeability transition pore via a fluorescent based counterscreen assay [AID651564, Type: confirmatory]
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5
[SID99361135]
uHTS identification of small molecule inhibitors of the mitochondrial permeability transition pore via an absorbance assay [AID602449, Type: screening]
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6
[SID99361135]
Potency 12.5893qHTS of PTHR Inhibitors: Primary Screen [AID743266, Type: confirmatory]parathyroid hormone/parathyroid hormone-related peptide receptor precursor [Homo sapiens] [gi:296080761]
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7
[SID99361135]
Potency qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen [AID720709, Type: confirmatory]Rap guanine nucleotide exchange factor 3 [gi:317373593]
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8
[SID99361135]
Potency qHTS for Agonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen [AID720707, Type: confirmatory]Rap guanine nucleotide exchange factor 3 [gi:317373593]
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9
[SID99361135]
Fluorescence polarization-based biochemical high throughput primary assay to identify inhibitors of alpha/beta hydrolase domain containing 4 (ABHD4). [AID720543, Type: screening]abhydrolase domain-containing protein 4 isoform 1 [Mus musculus] [gi:326937491]
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10
[SID99361135]
Potency qHTS for Inhibitors of KCHN2 3.1: Wildtype qHTS [AID720551, Type: confirmatory]potassium voltage-gated channel subfamily H member 2 isoform a [Homo sapiens] [gi:342840031]
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11
[SID99361135]
Potency qHTS for Inhibitors of KCHN2 3.1: Mutant qHTS [AID720553, Type: confirmatory]potassium voltage-gated channel subfamily H member 2 isoform a [Homo sapiens] [gi:342840031]
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12
[SID99361135]
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors of ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (ASAP1) [AID624377, Type: screening]arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform 2 [Homo sapiens] [gi:351542238]
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13
[SID99361135]
Mycobacterium tuberculosis BioA enzyme inhibitor Measured in Biochemical System Using Plate Reader - 2163-01_Inhibitor_SinglePoint_HTS_Activity [AID602481, Type: screening]bioA [Mycobacterium tuberculosis UT205] [gi:378544807]
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14
[SID99361135]
Potency qHTS of GLP-1 Receptor Inverse Agonists: Cytotox Screen [AID624418, Type: confirmatory]
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15
[SID99361135]
Counterscreen of compound fluorescence effects on High-throughput multiplex microsphere screening for inhibitors of toxin protease [AID624483, Type: screening]
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16
[SID99361135]
Single concentration confirmation of uHTS inhibitor hits of the mitochondrial permeability transition pore via a fluorescent based assay [AID624504, Type: screening]
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17
[SID99361135]
uHTS identification of small molecule Triacylglycerol inhbitors in a fluoresence assay [AID651582, Type: screening]
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18
[SID99361135]
HIV entry: Env-mediated Cell Fusion Measured in Cell-Based System Using Plate Reader - 7013-01_Inhibitor_SinglePoint_HTS_Activity [AID651610, Type: screening]
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19
[SID99361135]
DENV2 CPE-Based HTS Measured in Cell-Based and Microorganism Combination System Using Plate Reader - 2149-01_Other_SinglePoint_HTS_Activity [AID651640, Type: screening]
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20
[SID99361135]
HTS for the detection of C. neoformans cell lysis via adenylate kinase (AK) release Measured in Microorganism System Using Plate Reader - 2162-01_Inhibitor_SinglePoint_HTS_Activity [AID651654, Type: screening]
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