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CHEMBL1085745 (CID 46891217) - Compound BioActivity Data
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BioActivity Outcomes:
Active(6)
 
 
Unspecified(6)
 
 
Top Targets:
HAD like(2)
 
 
BioAssay Types:
Literature(12)
 
 
 
BioActivity Types:
IC50(8)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 12    Data Row: 12   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103758908]
IC50 0.007Inhibition of human soluble epoxide hydrolase [AID484177, Type: Literature]Bifunctional epoxide hydrolase 2 [gi:67476665]
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2
[SID103758908]
IC50 0.007Inhibition of human sEH [AID676944, Type: Literature]
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3
[SID103758908]
IC50 0.076Inhibition of human sEH by cell based assay [AID676945, Type: Literature]
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4
[SID103758908]
IC50 0.076Inhibition of human soluble epoxide hydrolase assessed as [2-3H]trans-1,3-diphenyl propylene oxide hydrolysis by cellular assay [AID484176, Type: Literature]Bifunctional epoxide hydrolase 2 [gi:67476665]
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5
[SID103758908]
IC50 0.3Inhibition of CYP2C9 [AID484180, Type: Literature]
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6
[SID103758908]
IC50 10Inhibition of CYP2J2 [AID484179, Type: Literature]
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7
[SID103758908]
IC50 0.3Inhibition of CYP2C9 [AID676947, Type: Literature]
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8
[SID103758908]
IC50 10Inhibition of CYP2J2 [AID676946, Type: Literature]
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9
[SID103758908]
Half life in human liver microsomes [AID676949, Type: Literature]
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10
[SID103758908]
Half life in rat liver microsomes [AID676950, Type: Literature]
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11
[SID103758908]
Half life in human liver microsome [AID484181, Type: Literature]
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12
[SID103758908]
Half life in mouse liver microsome [AID484182, Type: Literature]
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