CHEMBL1084437
(CID
46889696
) -
BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(
2
)
Unspecified(1)
BioAssay Types:
Literature(
3
)
BioActivity Types:
Ki(
2
)
SAR
Target summary
Data download
Chemical Probe
Active
Inactive
Inconclusive
Unspecified
Total Bioassays: 3 Data Row: 3 Total Pages: 1
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#
Substance
Activity
BioAssay
Target
Links
Outcome
Type
Value [μM]
1
[SID
103756400
]
Active
Ki
0.00061
Displacement of [3H]substance P from human NK1 receptor expressed in CHO cells [AID
484398
, Type: Literature]
Substance-P receptor [gi:
128359
]
View
X
Row No.
1
Structure
Substance
SID
103756400
CID
46889696
Outcome
Active
Ki
0.00061 [uM]
BioAssay
Displacement of [3H]substance P from human NK1 receptor expressed in CHO cells
AID
484398
BioAssay type
Literature
Target
Substance-P receptor [gi:
128359
]
PubMed
20430616
Data Table
2
[SID
103756400
]
Active
Ki
0.00061
Displacement of [3H]substance P from human NK1 receptor expressed in CHO cells [AID
484398
, Type: Literature]
Substance-P receptor [gi:
128359
]
View
X
Row No.
2
Structure
Substance
SID
103756400
CID
46889696
Outcome
Active
Ki
0.00061 [uM]
BioAssay
Displacement of [3H]substance P from human NK1 receptor expressed in CHO cells
AID
484398
BioAssay type
Literature
Target
Substance-P receptor [gi:
128359
]
PubMed
20430616
Data Table
3
[SID
103756400
]
Active
Ki
0.00112
Displacement of [3H]SR142801 from human NK3 receptor expressed in HEK293-EBNA cells [AID
484399
, Type: Literature]
Neuromedin-K receptor [gi:
128364
]
View
X
Row No.
3
Structure
Substance
SID
103756400
CID
46889696
Outcome
Active
Ki
0.00112 [uM]
BioAssay
Displacement of [3H]SR142801 from human NK3 receptor expressed in HEK293-EBNA cells
AID
484399
BioAssay type
Literature
Target
Neuromedin-K receptor [gi:
128364
]
PubMed
20430616
Data Table
4
[SID
103756400
]
Unspecified
Inhibition of GR-73632-induced foot tapping behavior in po dosed Mongolian gerbil administered 2 hrs before GR-73632 challenge [AID
484400
, Type: Literature]
View
X
Row No.
4
Structure
Substance
SID
103756400
CID
46889696
Outcome
Unspecified
BioAssay
Inhibition of GR-73632-induced foot tapping behavior in po dosed Mongolian gerbil administered 2 hrs before GR-73632 challenge
AID
484400
BioAssay type
Literature
Target
PubMed
20430616
Data Table