CHEMBL1083257
(CID
46830492
) -
BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(
3
)
BioAssay Types:
Literature(
3
)
BioActivity Types:
EC50(
3
)
SAR
Target summary
Data download
Chemical Probe
Active
Inactive
Inconclusive
Unspecified
Total Bioassays: 3 Data Row: 3 Total Pages: 1
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#
Substance
Activity
BioAssay
Target
Links
Outcome
Type
Value [μM]
1
[SID
103757149
]
Active
EC50
0.063
Agonist activity at human recombinant P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production by scintillation proximity assay [AID
484784
, Type: Literature]
P2Y purinoceptor 6 [gi:
2495018
]
View
X
Row No.
1
Structure
Substance
SID
103757149
CID
46830492
Outcome
Active
EC50
0.063 [uM]
BioAssay
Agonist activity at human recombinant P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production by scintillation proximity assay
AID
484784
BioAssay type
Literature
Target
P2Y purinoceptor 6 [gi:
2495018
]
PubMed
20446735
Data Table
2
[SID
103757149
]
Active
EC50
0.56
Agonist activity at human recombinant P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production by scintillation proximity assay [AID
484777
, Type: Literature]
P2Y purinoceptor 4 [gi:
1709524
]
View
X
Row No.
2
Structure
Substance
SID
103757149
CID
46830492
Outcome
Active
EC50
0.56 [uM]
BioAssay
Agonist activity at human recombinant P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production by scintillation proximity assay
AID
484777
BioAssay type
Literature
Target
P2Y purinoceptor 4 [gi:
1709524
]
PubMed
20446735
Data Table
3
[SID
103757149
]
Active
EC50
2.12
Agonist activity at human recombinant P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production by scintillation proximity assay [AID
484783
, Type: Literature]
P2Y purinoceptor 2 [gi:
311033490
]
View
X
Row No.
3
Structure
Substance
SID
103757149
CID
46830492
Outcome
Active
EC50
2.12 [uM]
BioAssay
Agonist activity at human recombinant P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production by scintillation proximity assay
AID
484783
BioAssay type
Literature
Target
P2Y purinoceptor 2 [gi:
311033490
]
PubMed
20446735
Data Table