Bookmark and Share
dexpanthenol (CID 4678) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(3)
 
 
Inactive(562)
 
 
Inconclusive(6)
 
 
Unspecified(133)
 
 
Top Targets:
7tm 4(68)
 
 
 
 
p450(10)
 
 
 
NR LBD ER(9)
 
 
 
NR LBD PPAR(8)
 
 
 
NR LBD AR(8)
 
 
 
BioAssay Types:
Screening(349)
 
 
 
Confirmatory(288)
 
 
 
 
Summary(24)
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(177)
 
 
 
 
IC50(127)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 662    Data Row: 704   Total Pages: 36   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56323427]
Aqueous Solubility from MLSMR Stock Solutions [AID1996, Type: other]
View
2
[SID48415866]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
View
3
[SID56320906]
Luminescence-based cell-based primary high throughput screening assay to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) [AID624169, Type: screening]5-hydroxytryptamine receptor 2A [Mus musculus] [gi:27753985]
View
4
[SID160693300]
IC50 DRUGMATRIX: Estrogen ERbeta radioligand binding (ligand: [3H] Estradiol) [AID625259, Type: confirmatory]Estrogen receptor beta [gi:6166154]
View
5
[SID160693300]
IC50 DRUGMATRIX: Cysteinyl leukotriene receptor 1 radioligand binding (ligand: [3H]LTD4) [AID625145, Type: confirmatory]Cysteinyl leukotriene receptor 1 [gi:20138087]
View
6
[SID160693300]
IC50 DRUGMATRIX: Muscarinic M4 radioligand binding (ligand: [3H] N-Methylscopolamine) [AID625154, Type: confirmatory]Muscarinic acetylcholine receptor M4 [gi:23503039]
View
7
[SID160693300]
DRUGMATRIX: Protein Tyrosine Phosphatase, PTPRC (CD45) enzyme inhibition (substrate: DiFMUP) [AID625188, Type: other]Receptor-type tyrosine-protein phosphatase C [gi:33112650]
View
8
[SID160693300]
IC50 DRUGMATRIX: Melanocortin MC4 radioligand binding (ligand: [125I] NDP-alpha-MSH) [AID625148, Type: confirmatory]Melanocortin receptor 4 [gi:60392672]
View
9
[SID160693300]
IC50 DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625247, Type: confirmatory]Cytochrome P450 2C19 [gi:60416369]
View
10
[SID160693300]
IC50 DRUGMATRIX: Sigma1 radioligand binding (ligand: [3H] Haloperidol) [AID625223, Type: confirmatory]Sigma non-opioid intracellular receptor 1 [gi:74752153]
View
11
[SID160693300]
IC50 DRUGMATRIX: Progesterone radioligand binding (ligand: [3H] R-5020) [AID625172, Type: confirmatory]Progesterone receptor [gi:75071465]
View
12
[SID160693300]
IC50 DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625248, Type: confirmatory]Cytochrome P450 2C9 [gi:6686268]
View
13
[SID160693300]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT4 radioligand binding (ligand: [3H] GR-113808) [AID625220, Type: confirmatory]5-hydroxytryptamine receptor 4 [gi:6224984]
View
14
[SID160693300]
IC50 DRUGMATRIX: Potassium Channel HERG radioligand binding (ligand: [3H] Astemizole) [AID625171, Type: confirmatory]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
View
15
[SID160693300]
IC50 DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912) [AID625203, Type: confirmatory]Alpha-2C adrenergic receptor [gi:20141211]
View
16
[SID160693300]
IC50 DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625249, Type: confirmatory]Cytochrome P450 2D6 [gi:84028191]
View
17
[SID160693300]
IC50 DRUGMATRIX: Vascular Endothelial Growth Factor (VEGF) radioligand binding (ligand: [125I] VEGF) [AID625231, Type: confirmatory]Vascular endothelial growth factor receptor 1 [gi:143811474]
View
18
[SID160693300]
IC50 DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin) [AID625251, Type: confirmatory]Cytochrome P450 3A4 [gi:116241312]
View
19
[SID160693300]
IC50 DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine) [AID625162, Type: confirmatory]Kappa-type opioid receptor [gi:116242691]
View
20
[SID160693300]
DRUGMATRIX: Chemokine CXCR1 (IL-8A) [AID625240, Type: other]C-X-C chemokine receptor type 1 [gi:108936015]
View