CHEMBL1813478 (CID 46701016) - BioAssay Data Summary for Compound
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BioActivity Outcomes:
Active(9)
 
 
Top Targets:
p450(4)
 
 
CAP ED(1)
 
 
BioAssay Types:
Literature(9)
 
 
BioActivity Types:
IC50(9)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 9    Data Row: 9   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID134436219]
IC50 0.00891Inhibition of serotonin reuptake at SERT expressed in HEK293 cells [AID611191, Type: Literature]
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2
[SID134436219]
IC50 0.02399Inhibition of norepinephrine reuptake at NET expressed in MDCK cells [AID611192, Type: Literature]
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3
[SID134436219]
IC50 0.06761Inhibition of dopamine reuptake at DAT expressed in CHO-K1 cells [AID611193, Type: Literature]
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4
[SID134436219]
IC50 1.49Inhibition of CYP1A in human liver microsomes by LC-MS/MS analysis [AID611196, Type: Literature]
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5
[SID134436219]
IC50 2.22Inhibition of CYP2C19 in human liver microsomes by LC-MS/MS analysis [AID611198, Type: Literature]Cytochrome P450 2C19 [gi:60416369]
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6
[SID134436219]
IC50 2.22Inhibition of CYP2C19 in human liver microsomes by LC-MS/MS analysis [AID611198, Type: Literature]Cytochrome P450 2C19 [gi:60416369]
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7
[SID134436219]
IC50 4.35Inhibition of CYP2D6 in human liver microsomes by LC-MS/MS analysis [AID611199, Type: Literature]Cytochrome P450 2D6 [gi:84028191]
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8
[SID134436219]
IC50 4.35Inhibition of CYP2D6 in human liver microsomes by LC-MS/MS analysis [AID611199, Type: Literature]Cytochrome P450 2D6 [gi:84028191]
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9
[SID134436219]
IC50 5.64Inhibition of human ERG expressed in CHO cells by high throughput single cell planar patch clamp method [AID611281, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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10
[SID134436219]
IC50 5.64Inhibition of human ERG expressed in CHO cells by high throughput single cell planar patch clamp method [AID611281, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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11
[SID134436219]
IC50 5.64Inhibition of human ERG expressed in CHO cells by high throughput single cell planar patch clamp method [AID611281, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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12
[SID134436219]
IC50 5.64Inhibition of human ERG expressed in CHO cells by high throughput single cell planar patch clamp method [AID611281, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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13
[SID134436219]
IC50 5.64Inhibition of human ERG expressed in CHO cells by high throughput single cell planar patch clamp method [AID611281, Type: Literature]Potassium voltage-gated channel subfamily H member 2 [gi:7531135]
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14
[SID134436219]
IC50 9.83Inhibition of CYP2C9 in human liver microsomes by LC-MS/MS analysis [AID611197, Type: Literature]Cytochrome P450 2C9 [gi:6686268]
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15
[SID134436219]
IC50 9.83Inhibition of CYP2C9 in human liver microsomes by LC-MS/MS analysis [AID611197, Type: Literature]Cytochrome P450 2C9 [gi:6686268]
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16
[SID134436219]
IC50 9.83Inhibition of CYP2C9 in human liver microsomes by LC-MS/MS analysis [AID611197, Type: Literature]Cytochrome P450 2C9 [gi:6686268]
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17
[SID134436219]
IC50 12.7Inhibition of CYP3A4 in human liver microsomes by LC-MS/MS analysis [AID611280, Type: Literature]Cytochrome P450 3A4 [gi:116241312]
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18
[SID134436219]
IC50 12.7Inhibition of CYP3A4 in human liver microsomes by LC-MS/MS analysis [AID611280, Type: Literature]Cytochrome P450 3A4 [gi:116241312]
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19
[SID134436219]
IC50 12.7Inhibition of CYP3A4 in human liver microsomes by LC-MS/MS analysis [AID611280, Type: Literature]Cytochrome P450 3A4 [gi:116241312]
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