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BioActivity Data for Compound SMR000620332 (CID 46500291)

BioActivity Outcomes:
Active(6)
 
 
Inactive(525)
 
 
Inconclusive(13)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(37)
 
 
TRP 2(5)
 
 
Esterase lipa..(5)
 
 
CAP ED(5)
 
 
 
Pyruvate Kina..(4)
 
 
BioAssay Types:
Screening(372)
 
 
 
Confirmatory(159)
 
 
 
 
 
Literature(11)
 
 
BioAssay Categories:
In vivo(1)
 
 
Biochemical(115)
 
 
 
Toxicity(5)
 
 
 
Cell-based(115)
 
 
Organism-base..(13)
 
 
BioActivity Types:
Potency(122)
 
 
 
 
 
IC50(28)
 
 
EC50(4)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 497    Data Row: 545   Total Pages: 28   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID49714864]
EC50 3.40981Image-based HTS for Selective Agonists of GPR55 [AID1961, Type: confirmatory]G-protein coupled receptor 55 [Homo sapiens] [gi:33695107]
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2
[SID49714864]
AbsAC1_uM 14.01Small Molecule Inhibitors of FGF22-Mediated Excitatory Synaptogenesis & Epilepsy Measured in Biochemical System Using RT-PCR - 7012-01_Inhibitor_Dose_CherryPick_Activity [AID687022, Type: confirmatory]fibroblast growth factor 22 isoform 1 precursor [Homo sapiens] [gi:10190672]
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3
[SID49714864]
Potency 23.1093Nrf2 qHTS screen for inhibitors [AID504444, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
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4
[SID49714864]
Potency qHTS for Inhibitors of KCHN2 3.1: Mutant qHTS [AID720553, Type: confirmatory]potassium voltage-gated channel subfamily H member 2 isoform a, partial [Homo sapiens] [gi:342840031]
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5
[SID49714864]
Phenotypic HTS multiplex for antifungal efflux pump inhibitors [AID485275, Type: screening]
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6
[SID49714864]
Small Molecule Inhibitors of FGF22-Mediated Excitatory Synaptogenesis & Epilepsy Measured in Biochemical System Using RT-PCR - 7012-01_Inhibitor_SinglePoint_HTS_Activity [AID651658, Type: screening]fibroblast growth factor 22 isoform 1 precursor [Homo sapiens] [gi:10190672]
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7
[SID49714864]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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8
[SID49714864]
Heat Shock Factor-1 (HSF-1) Measured in Cell-Based System Using Plate Reader - 2038-01_Activator_SinglePoint_HTS_Activity [AID504408, Type: screening]
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9
[SID49714864]
AbsAC0.54_uM Small Molecule Inhibitors of FGF22-Mediated Excitatory Synaptogenesis & Epilepsy Measured in Biochemical System Using RT-PCR - 7012-03_Inhibitor_Dose_CherryPick_Activity [AID743019, Type: confirmatory]fibroblast growth factor 22 isoform 1 precursor [Homo sapiens] [gi:10190672]
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10
[SID49714864]
AbsAC0.39_uM Small Molecule Inhibitors of FGF22-Mediated Excitatory Synaptogenesis & Epilepsy Measured in Biochemical System Using RT-PCR - 7012-04_Inhibitor_Dose_CherryPick_Activity [AID720646, Type: confirmatory]fibroblast growth factor 22 isoform 1 precursor [Homo sapiens] [gi:10190672]
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11
[SID49714864]
Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ LAP4_MLPCN. [AID2023, Type: screening]LAP4 [Saccharomyces cerevisiae] [gi:486173]
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12
[SID49714864]
Primary cell-based high-throughput screening assay for identification of compounds that protect hERG from block by proarrhythmic agents [AID1511, Type: screening]putative potassium channel subunit [Homo sapiens] [gi:487738]
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13
[SID49714864]
Potency qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease [AID2101, Type: confirmatory]glucocerebrosidase [Homo sapiens] [gi:496369]
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14
[SID49714864]
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL). [AID2129, Type: screening]bcl-xL [Homo sapiens] [gi:510901]
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15
[SID49714864]
Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ RPL19A_MLPCN. [AID2025, Type: screening]RPL19A [Saccharomyces cerevisiae] [gi:536029]
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16
[SID49714864]
Potency Activators of T cell receptors: qHTS campaign [AID504894, Type: confirmatory]T cell receptor, partial [Homo sapiens] [gi:553160]
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17
[SID49714864]
Potency qHTS of alpha-syn Inhibitors [AID652106, Type: confirmatory]Alpha-synuclein [gi:586067]
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18
[SID49714864]
Potency qHTS of Nrf2 Activators [AID624171, Type: confirmatory]Nrf2 [Homo sapiens] [gi:693842]
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19
[SID49714864]
Fluorescence Cell-Based Primary HTS of C.albicans growth in the presence of Fluconazole and compound [AID1979, Type: screening]heat shock protein 90 [Candida albicans] [gi:994798]
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20
[SID49714864]
HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_SinglePoint_HTS_Activity [AID652154, Type: screening]PAX8 [Homo sapiens] [gi:998701]
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