Bookmark and Share
MLS000686374 (CID 46500142) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(16)
 
 
Inactive(672)
 
 
Inconclusive(27)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
 
7TM GPCR Srsx(17)
 
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
Tryp SPc(7)
 
 
BioAssay Types:
Screening(489)
 
 
 
 
Confirmatory(198)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(142)
 
 
 
 
 
IC50(42)
 
 
 
EC50(8)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 646    Data Row: 716   Total Pages: 36   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID24813113]
Potency 14.1254qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding [AID1460, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
View
2
[SID24813113]
Potency 26.6795qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]serine/threonine-protein kinase PLK1 [Homo sapiens] [gi:21359873]
View
3
[SID24813113]
uHTS Identification of Diaphorase Inhibitors and Chemcical Oxidizers: Counter Screen for Diaphorase-based Primary Assays [AID1217, Type: screening]Dihydrolipoamide dehydrogenase [Homo sapiens] [gi:17391426]
View
4
[SID24813113]
Multiplex HTS Assay for Inhibitors of MEK Kinase PB1 Domains, specifically MEK5 binding to MEK Kinase 2 Wildtype [AID1531, Type: screening]mitogen-activated protein kinase kinase kinase kinase 2 [Homo sapiens] [gi:22035600]
View
5
[SID24813113]
uHTS identification of small molecule antagonists of the CCR6 receptor via a luminescent beta-arrestin assay [AID493098, Type: screening]C-C chemokine receptor type 6 [Homo sapiens] [gi:37187860]
View
6
[SID24813113]
Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Primary Screen [AID1456, Type: other]electroneutral potassium-chloride cotransporter KCC2 [Homo sapiens] [gi:12003227]
View
7
[SID24813113]
uHTS Fluorescent Assay Using Nedd8 Protein Substrate for Identification of Inhibitors of Sentrin-Specific Protease 8 (SENP8) [AID602440, Type: screening]sentrin-specific protease 8 [Homo sapiens] [gi:262118306]
View
8
[SID24813113]
MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - activators [AID1814, Type: screening]
View
9
[SID24813113]
Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Counterscreen with HEK cells [AID1716, Type: other]
View
10
[SID24813113]
Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Retesting of KCC2 cells with Ouabain [AID1717, Type: other]
View
11
[SID24813113]
Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Secondary Assay 3 with KCC2 cells [AID1714, Type: other]electroneutral potassium-chloride cotransporter KCC2 [Homo sapiens] [gi:12003227]
View
12
[SID24813113]
uHTS identification of small molecule inhibitors of the catalytic domain of the SUMO protease, SENP1 in a FRET assay [AID624204, Type: screening]sentrin-specific protease 1 [Homo sapiens] [gi:7657550]
View
13
[SID24813113]
Primary cell-based high throughput screening assay to measure STAT3 activation [AID871, Type: screening]STAT3, partial [Homo sapiens] [gi:13272532]
View
14
[SID24813113]
Confirmation cell-based high throughput screening assay to measure STAT3 activation [AID1267, Type: screening]STAT3, partial [Homo sapiens] [gi:13272532]
View
15
[SID24813113]
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_SinglePoint_HTS_Activity [AID488896, Type: screening]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
View
16
[SID24813113]
IC50 HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay using a high concentration of mannose 6-phosphate [AID1220, Type: confirmatory]MPI protein [Homo sapiens] [gi:16878311]
View
17
[SID24813113]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
18
[SID24813113]
Potency 11.2202qHTS of GLP-1 Receptor Inverse Agonists: Cytotox Screen [AID624418, Type: confirmatory]
View
19
[SID24813113]
Potency 28.1838qHTS for Inhibitors of ATXN expression [AID651635, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
View
20
[SID24813113]
uHTS Fluorescent assay for identification of inhibitors of Apaf-1 [AID489030, Type: screening]Apoptotic peptidase activating factor 1 [Homo sapiens] [gi:187952397]
View