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MLS000722889 (CID 46495353) - Compound BioActivity Data
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BioActivity Outcomes:
Active(15)
 
 
Inactive(670)
 
 
Inconclusive(8)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
7TM GPCR Srsx(14)
 
 
Bcl-2 like(11)
 
 
KCNQ channel(10)
 
 
 
alkPPc(10)
 
 
BioAssay Types:
Screening(468)
 
 
 
 
Confirmatory(197)
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(144)
 
 
 
 
IC50(39)
 
 
EC50(8)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 628    Data Row: 694   Total Pages: 35   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID24823215]
Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Counterscreen with HEK cells [AID1716, Type: other]
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2
[SID24823215]
Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Retesting of KCC2 cells with Ouabain [AID1717, Type: other]
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3
[SID24823215]
Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Counterscreen 2 with HEK cells [AID1718, Type: other]
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4
[SID24823215]
Primary cell-based high-throughput screening assay for identification of compounds that protect hERG from block by proarrhythmic agents [AID1511, Type: screening]putative potassium channel subunit [Homo sapiens] [gi:487738]
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5
[SID24823215]
Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Secondary Assay with KCC2 cells [AID1713, Type: other]electroneutral potassium-chloride cotransporter KCC2 [Homo sapiens] [gi:12003227]
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6
[SID24823215]
Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Secondary Assay 3 with KCC2 cells [AID1714, Type: other]electroneutral potassium-chloride cotransporter KCC2 [Homo sapiens] [gi:12003227]
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7
[SID24823215]
Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Secondary Assay 2 with KCC2 cells [AID1715, Type: other]electroneutral potassium-chloride cotransporter KCC2 [Homo sapiens] [gi:12003227]
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8
[SID24823215]
Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Primary Screen [AID1456, Type: other]electroneutral potassium-chloride cotransporter KCC2 [Homo sapiens] [gi:12003227]
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9
[SID24823215]
Small Molecule Inhibitors of FGF22-Mediated Excitatory Synaptogenesis & Epilepsy Measured in Biochemical System Using RT-PCR - 7012-01_Inhibitor_SinglePoint_HTS_Activity [AID651658, Type: screening]fibroblast growth factor 22 isoform 1 precursor [Homo sapiens] [gi:10190672]
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10
[SID24823215]
KCNQ2 Counter screen for compounds that protect hERG from block by proarrhythmic agents [AID1942, Type: screening]potassium voltage-gated channel subfamily KQT member 2 [Rattus norvegicus] [gi:18959272]
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11
[SID24823215]
Specificity screen assay against KCNQ2 for identification of compounds that potentiate KCNQ1 potassium channels [AID493009, Type: screening]potassium voltage-gated channel subfamily KQT member 2 [Rattus norvegicus] [gi:18959272]
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12
[SID24823215]
Primary cell-based high-throughput screening assay for identification of compounds that potentiate/activate KCNQ1 potassium channels [AID2648, Type: screening]potassium voltage-gated channel subfamily KQT member 1 isoform 1 [Homo sapiens] [gi:32479527]
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13
[SID24823215]
Counter screen assay of the parental CHO cells for identification of compounds that potentiate KCNQ1 potassium channels [AID493006, Type: screening]potassium voltage-gated channel subfamily KQT member 1 isoform 1 [Homo sapiens] [gi:32479527]
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14
[SID24823215]
Validation assay for identification of compounds that potentiate KCNQ1 potassium channels [AID493007, Type: screening]potassium voltage-gated channel subfamily KQT member 1 isoform 1 [Homo sapiens] [gi:32479527]
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15
[SID24823215]
Confirmatory screen for compounds that protect hERG from block by proarrhythmic agents [AID1835, Type: screening]putative potassium channel subunit [Homo sapiens] [gi:487738]
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16
[SID24823215]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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17
[SID24823215]
Potency 0.7943qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS [AID624288, Type: confirmatory]Guanine nucleotide-binding protein G(s) subunit alpha isoforms short [gi:52000961]
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18
[SID24823215]
Potency 1.5849qHTS for Inhibitors of AMA1-RON; Towards Development of Antimalarial Drug Lead: Primary Screen [AID720542, Type: confirmatory]apical membrane antigen 1, AMA1 [Plasmodium falciparum 3D7] [gi:23496270]
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19
[SID24823215]
QFRET-based primary biochemical high throughput screening assay to identify inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP). [AID1822, Type: screening]M18 aspartyl aminopeptidase [Plasmodium falciparum 3D7] [gi:23505220]
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20
[SID24823215]
Epi Absorbance-based biochemical primary high throughput screening assay to identify inhibitors of human tyrosyl-DNA phosphodiesterase 2 (TDP2) [AID720702, Type: screening]tyrosyl-DNA phosphodiesterase 2 [Homo sapiens] [gi:23510348]
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