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2-(Methylamino)-1,4-naphthoquinone (CID 464135) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(7)
 
 
Inactive(5)
 
 
Unspecified(4)
 
 
BioAssay Types:
Confirmatory(10)
 
 
 
Literature(6)
 
 
 
 
BioActivity Types:
AC50(10)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 16    Data Row: 16   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103544386]
PD50 1.346Neuroprotective activity in mouse HT22 cells assessed as prevention from glutamate-induced oxidative cell death by MTS assay [AID736844, Type: Literature]
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2
[SID135724468]
AC50_uM 9.17MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_Dose_DryPowder_Activity_Set5 [AID624363, Type: confirmatory]
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3
[SID135724468]
AC50_uM 11.29MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_Dose_DryPowder_Activity_Set6 [AID624440, Type: confirmatory]
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4
[SID135724468]
AC50_uM 17.2MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_Dose_DryPowder_Activity_Set7 [AID624426, Type: confirmatory]
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5
[SID135724468]
AC50_uM 52.88MITF Orthogonal Assay: SK-MEL-5 CTG Assay Measured in Cell-Based System Using Plate Reader - 2084-02_Inhibitor_Dose_DryPowder_Activity_Set5 [AID624427, Type: confirmatory]
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6
[SID135724468]
AC50_uM 54.17MITF Orthogonal Assay: MALME3 CTG Assay Measured in Cell-Based System Using Plate Reader - 2084-04_Inhibitor_Dose_DryPowder_Activity_Set3 [AID624362, Type: confirmatory]
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7
[SID135724468]
AC50_uM 62.62MITF Orthogonal Assay: SK-MEL-5 CTG Assay Measured in Cell-Based System Using Plate Reader - 2084-02_Inhibitor_Dose_DryPowder_Activity_Set6 [AID624429, Type: confirmatory]
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8
[SID103544386]
TC50 100Neurotoxicity in mouse HT22 cells assessed as cell viability after 24 hrs by MTS assay [AID736842, Type: Literature]
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9
[SID103544386]
Therapeutic index, ratio of cytotoxic TC50 for mouse HT22 cells to neuroprotective PD50 for mouse HT22 cells [AID736843, Type: Literature]
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10
[SID103414985]
HPLC capacity factor (logK) [AID19426, Type: Literature]
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11
[SID103414985]
Partition coefficient (logP) [AID19838, Type: Literature]
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12
[SID135724468]
AC50_uM 70MITF Orthogonal Assay: SK-MEL-5 CTG Assay Measured in Cell-Based System Using Plate Reader - 2084-02_Inhibitor_Dose_DryPowder_Activity_Set4 [AID624366, Type: confirmatory]
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13
[SID135724468]
AC50_uM 70MITF: Counter assay: A375 proliferation Measured in Cell-Based System Using Plate Reader - 2084-03_Inhibitor_Dose_DryPowder_Activity_Set7 [AID624490, Type: confirmatory]
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14
[SID103544386]
Inhibition of pig pancreatic elastase [AID308238, Type: Literature]
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15
[SID135724468]
AC50_uM MITF: Counter assay: A375 proliferation Measured in Cell-Based System Using Plate Reader - 2084-03_Inhibitor_Dose_DryPowder_Activity_Set5 [AID624368, Type: confirmatory]
View
16
[SID135724468]
AC50_uM MITF: Counter assay: A375 proliferation Measured in Cell-Based System Using Plate Reader - 2084-03_Inhibitor_Dose_DryPowder_Activity_Set6 [AID624488, Type: confirmatory]
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