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1H-Naphtho[2,1-b]pyran-1-one, 3-(2-fluorophenyl)- (CID 46232107) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Unspecified(3)
 
 
Top Targets:
PAS(2)
 
 
BioAssay Types:
Literature(5)
 
 
 
BioActivity Types:
EC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 5   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103727576]
EC50 0.33Agonist activity at aryl hydrocarbon receptor in human MCF7 cells after 24 hrs CYP1A1-dependent EROD assay [AID458180, Type: Literature]Aryl hydrocarbon receptor [gi:3041653]
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2
[SID103727576]
EC50 0.33Agonist activity at AhR in human MCF-7 cells assessed as increase of CYP1A1-dependent 7-ethoxyresorufin O-deethylase activity [AID600453, Type: Literature]Aryl hydrocarbon receptor [gi:3041653]
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3
[SID103727576]
Thermodynamic aqueous solubility in equal volume of ethyl alcohol and 1/15M phosphate buffer at pH 7.4 [AID458181, Type: Literature]
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4
[SID103727576]
Toxicity in human MCF7 cells assessed as effect on cell viability after 24 hrs [AID458182, Type: Literature]
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5
[SID103727576]
Thermodynamic aqueous solubility of the compound in ethanol/phosphate buffer at pH 7.4 [AID600454, Type: Literature]
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