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CHEMBL1091815 (CID 46180761) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(8)
 
 
Inconclusive(3)
 
 
BioAssay Types:
Literature(11)
 
 
 
BioActivity Types:
IC50(11)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 11    Data Row: 11   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103740187]
IC50 0.0014Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrs [AID465151, Type: Literature]
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2
[SID103740187]
IC50 0.0017Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrs [AID465154, Type: Literature]
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3
[SID103740187]
IC50 0.0053Inhibition of HDAC1 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrs [AID465149, Type: Literature]
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4
[SID103740187]
IC50 0.4Growth inhibition of human HUPT3 cells after 72 hrs by MTS assay [AID465156, Type: Literature]
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5
[SID103740187]
IC50 0.8Growth inhibition of human MIAPaCa2 cells after 72 hrs by MTS assay [AID465157, Type: Literature]
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6
[SID103740187]
IC50 1.2Growth inhibition of human BxPC3 cells after 72 hrs by MTS assay [AID465155, Type: Literature]
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7
[SID103740187]
IC50 1.7Growth inhibition of human SU-8686 cells after 72 hrs by MTS assay [AID465159, Type: Literature]
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8
[SID103740187]
IC50 2.03Growth inhibition of human Panc 04.03 cells after 72 hrs by MTS assay [AID465158, Type: Literature]
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9
[SID103740187]
IC50 Inhibition of HDAC2 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrs [AID465150, Type: Literature]
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10
[SID103740187]
IC50 Inhibition of HDAC8 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrs [AID465152, Type: Literature]
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11
[SID103740187]
IC50 Inhibition of HDAC10 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrs [AID465153, Type: Literature]
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