Bookmark and Share
STK397048 (CID 460749) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(196)
 
 
Inactive(417)
 
 
Inconclusive(54)
 
 
Unspecified(5)
 
 
Top Targets:
alkPPc(14)
 
 
Bcl-2 like(13)
 
 
 
7TM GPCR Srx(12)
 
 
 
 
7TM GPCR Srsx(11)
 
 
 
G-alpha(6)
 
 
 
BioAssay Types:
Screening(394)
 
 
 
 
 
Confirmatory(232)
 
 
 
 
 
Literature(33)
 
 
 
 
BioActivity Types:
Potency(137)
 
 
 
 
 
IC50(63)
 
 
 
 
 
EC50(24)
 
 
 
 
AC50(5)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 625    Data Row: 672   Total Pages: 34   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID14723875]
EC50_uM 0.0305Fluorescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of RecA-Intein Splicing Activity [AID435010, Type: confirmatory]recombinase A [Mycobacterium tuberculosis H37Rv] [gi:15609874]
View
2
[SID14723875]
IC50 0.039SMAD Transcription Factor Inhibitors Dose Response Confirmation [AID715, Type: confirmatory]mothers against decapentaplegic homolog 3 isoform 1 [Homo sapiens] [gi:5174513]
View
3
[SID14723875]
AC50_uM 0.0409Fluorescence Cell-Free Homogeneous Secondary Screen to Identify Inhibitors of DnaB-Intein Splicing Activity [AID449749, Type: confirmatory]replicative DNA helicase [Mycobacterium tuberculosis H37Rv] [gi:15607200]
View
4
[SID14723875]
AC50_uM 0.0579Fluorescence Cell-Free Homogeneous Secondary Screen to Identify Non-Covalent Inhibitors of RecA-Intein Splicing Activity [AID449750, Type: confirmatory]replicative DNA helicase [Mycobacterium tuberculosis H37Rv] [gi:15607200]
View
5
[SID14723875]
IC50 0.11102Luminescence-based counterscreen for inhibitors of the SARS coronavirus 3C-like Protease (3CLPro): dose response biochemical high throughput screening assay to identify inhibitors of the papain-like protease (PLpro) [AID1944, Type: confirmatory]
View
6
[SID85736034]
Potency 0.1296qHTS of small molecules that selectively kill Giardia lamblia: Hit Validation. [AID588397, Type: confirmatory]
View
7
[SID14723875]
Potency 0.259qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding: Initial hit validation in AlphaScreen assay for MBNL1-(CUG)12 binding [AID493205, Type: confirmatory]muscleblind-like protein 1 isoform a [Homo sapiens] [gi:41281591]
View
8
[SID164141672]
IC50 0.3Inhibition of human TCF4/ flag epitope-tagged beta-catenin (unknown origin) interaction transfected in human HCT116 cells after 24 hrs by beta-galactosidase/luciferase reporter gene assay [AID775767, Type: Literature]Transcription factor 7-like 2 [gi:29337146]
View
9
[SID164141672]
IC50 0.3Inhibition of human TCF4/ flag epitope-tagged beta-catenin (unknown origin) interaction transfected in human HCT116 cells after 24 hrs by beta-galactosidase/luciferase reporter gene assay [AID775767, Type: Literature]Catenin beta-1 [gi:461854]
View
10
[SID14723875]
EC50_uM 0.3648Fluorescence Cell-Free Homogeneous Counter Screen to Identify Inhibitors of GFP Chromophore Formation [AID434968, Type: confirmatory]recombinase A [Mycobacterium tuberculosis H37Rv] [gi:15609874]
View
11
[SID14723875]
IC50 0.396Fluorescence dose response cell-based high throughput screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4) [AID1692, Type: confirmatory]Sphingosine-1-phosphate receptor 4 [Homo sapiens] [gi:15929025]
View
12
[SID14723875]
AC50_uM 0.4409Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Beta Cell Apoptosis [AID449756, Type: confirmatory]
View
13
[SID14723875]
AC50_uM 0.5085ATP-based Luminescence in the Absence of Cytokines Measured in Cell-Based System Using Plate Reader - 2061-06_Inhibitor_Dose_CherryPick [AID463229, Type: confirmatory]
View
14
[SID14723875]
IC50 0.634Counterscreen for S1P2 Antagonists: Dose Response Cell-Based Screen to Identify Antagonists of CRE-BLA [AID856, Type: confirmatory]sphingosine 1-phosphate receptor 2 [Homo sapiens] [gi:134244587]
View
15
[SID14723875]
Potency 0.6506qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding: Initial hit validation from the primary screen [AID493199, Type: confirmatory]muscleblind-like protein 1 isoform a [Homo sapiens] [gi:41281591]
View
16
[SID14723875]
DR EC50 uM 0.89NIH Compound Library Profiling: Compound and DTT Dependent Redox Cycling H2O2 Generation 10-point Concentration Response Confirmation Assay. [AID1234, Type: confirmatory]
View
17
[SID85736034]
Potency 0.8913Confirmation qHTS Assay for Inhibitors of Cruzain [AID2158, Type: confirmatory]Chain A, Crystal Structure Of Cruzain Covalently Bound To A Purine Nitrile [gi:281307097]
View
18
[SID14723875]
Potency 0.9285Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
View
19
[SID14723875]
IC50 0.996Dose Response Cell Based Assay for Antagonists of the S1P2 Receptor [AID851, Type: confirmatory]sphingosine 1-phosphate receptor 2 [Homo sapiens] [gi:134244587]
View
20
[SID14723875]
Potency 1qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction [AID1461, Type: confirmatory]neuropeptide S receptor isoform A [Homo sapiens] [gi:46395496]
View