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Guaiacol (CID 460) - Compound BioActivity Data
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BioActivity Outcomes:
Active(8)
 
 
Inactive(1387)
 
 
Inconclusive(53)
 
 
Unspecified(40)
 
 
Top Targets:
NR LBD PPAR(41)
 
 
 
NR LBD AR(34)
 
 
 
NR LBD ER(34)
 
 
 
NR LBD TR(24)
 
 
NR LBD GR(22)
 
 
 
BioAssay Types:
Confirmatory(872)
 
 
 
 
 
Screening(369)
 
 
Literature(124)
 
 
 
 
 
Summary(87)
 
 
 
BioActivity Types:
Potency(797)
 
 
 
 
 
IC50(29)
 
 
 
EC50(4)
 
 
Ki(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 775    Data Row: 1488   Total Pages: 75   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103176224]
Ki 2.94Inhibition of human erythrocyte CA2 esterase activity using 4-nitrophenyl acetate substrate [AID416126, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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2
[SID144213965]
Potency-Replicate_1 4.3541qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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3
[SID144213965]
Potency-Replicate_1 24.4757qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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4
[SID48416072]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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5
[SID103176224]
Decrease in Diplodia seriata (Schwein.) Shoemaker ligninolytic enzyme production assessed as pectinase activity using pectin as substrate at 15 mM measured at 28 degC after 4 days [AID1107732, Type: Literature]
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6
[SID103176224]
Decrease in Botryosphaeria dothidea ligninolytic enzyme production assessed as laccase activity using ABTS as substrate measured at 28 degC after 4 days [AID1107740, Type: Literature]
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7
[SID103176224]
Inhibition of Diplodia seriata (Schwein.) Shoemaker mycelium growth at 15 mM measured at 28 degC after 4 days [AID1107751, Type: Literature]
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8
[SID103176224]
Inhibition of Neofusicoccum ribis mycelium growth at 20 mM measured at 28 degC after 4 days [AID1107755, Type: Literature]
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9
[SID103176224]
Ki 60.2Inhibition of human erythrocyte CA1 esterase activity using 4-nitrophenyl acetate substrate [AID416125, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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10
[SID103176224]
IC50 6310Inhibitory activity on germination of Bacillus subtilis PCI219 spores was determined. [AID40623, Type: Literature]
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11
[SID103176224]
Inhibition of Bacillus subtilis PCI219 spore germination, expressed as log 1/I50 [AID40936, Type: Literature]
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12
[SID103176224]
Lipophilicity determined as logarithm of the partition coefficient in the alkane/water system [AID237685, Type: Literature]
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13
[SID103176224]
Activity against caspase-mediated apoptosis in mouse L1210 cells at 0.1 mM [AID282833, Type: Literature]
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14
[SID103176224]
Activity against caspase-mediated apoptosis in mouse L1210 cells [AID282834, Type: Literature]
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15
[SID103176224]
Antiinflammatory activity in CD1 mouse assessed as inhibition of croton oil-induced ear oedema at 0.3 umol/cm^2 after 6 hrs [AID309363, Type: Literature]
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16
[SID103176224]
Inhibition of mouse recombinant iNOS at 1 mM after 40 mins by colorimetric assay [AID566707, Type: Literature]Nitric oxide synthase, inducible [gi:266649]
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17
[SID103176224]
Decrease in Lasiodiplodia theobromae ligninolytic enzyme production assessed as laccase activity using ABTS as substrate at 1 mM measured at 28 degC after 4 days [AID1107741, Type: Literature]
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18
[SID103176224]
Decrease in Lasiodiplodia theobromae mycelium biomass production measured at 28 degC after 4 days by gravimetric analysis [AID1107745, Type: Literature]
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19
[SID103176224]
Decrease in Diplodia seriata (Schwein.) Shoemaker mycelium biomass production measured at 28 degC after 4 days by gravimetric analysis [AID1107746, Type: Literature]
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20
[SID103176224]
Feeding deterrent activity against freshly molted third-instar larval stage of Trichoplusia ni (cabbage looper), Trichoplusia ni at 50 ug/cm'2 after 3 to 5 hr by leaf disk choice bioassay [AID1090868, Type: Literature]
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