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BioActivity Data for Compound Guaiacol (CID 460)

BioActivity Outcomes:
Active(8)
 
 
Inactive(1439)
 
 
Inconclusive(59)
 
 
Unspecified(40)
 
 
Top Targets:
7tm 4(41)
 
 
NR LBD PPAR(41)
 
 
 
NR LBD ER(34)
 
 
 
NR LBD AR(34)
 
 
 
NR LBD TR(24)
 
 
BioAssay Types:
Confirmatory(909)
 
 
 
 
 
Screening(377)
 
 
Literature(124)
 
 
 
 
 
Summary(99)
 
 
 
BioAssay Categories:
In vivo(1)
 
 
Biochemical(126)
 
 
 
 
Toxicity(120)
 
 
 
 
ADME(8)
 
 
Cell-based(124)
 
 
 
Organism-base..(13)
 
 
BioActivity Types:
Potency(840)
 
 
 
 
 
IC50(29)
 
 
 
AC50(6)
 
 
EC50(4)
 
 
Ki(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 805    Data Row: 1546   Total Pages: 78   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103176224]
Ki 2.94Inhibition of human erythrocyte CA2 esterase activity using 4-nitrophenyl acetate substrate [AID416126, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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2
[SID144213965]
Potency-Replicate_1 4.3541qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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3
[SID144213965]
Potency-Replicate_1 24.4757qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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4
[SID103176224]
Inhibition of Diplodia seriata (Schwein.) Shoemaker mycelium growth at 15 mM measured at 28 degC after 4 days [AID1107751, Type: Literature]
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5
[SID103176224]
Decrease in Diplodia seriata (Schwein.) Shoemaker ligninolytic enzyme production assessed as pectinase activity using pectin as substrate at 15 mM measured at 28 degC after 4 days [AID1107732, Type: Literature]
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6
[SID103176224]
Decrease in Botryosphaeria dothidea ligninolytic enzyme production assessed as laccase activity using ABTS as substrate measured at 28 degC after 4 days [AID1107740, Type: Literature]
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7
[SID48416072]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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8
[SID103176224]
Inhibition of Neofusicoccum ribis mycelium growth at 20 mM measured at 28 degC after 4 days [AID1107755, Type: Literature]
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9
[SID103176224]
Ki 60.2Inhibition of human erythrocyte CA1 esterase activity using 4-nitrophenyl acetate substrate [AID416125, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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10
[SID103176224]
IC50 6310Inhibitory activity on germination of Bacillus subtilis PCI219 spores was determined. [AID40623, Type: Literature]
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11
[SID103176224]
Activity against caspase-mediated apoptosis in mouse L1210 cells [AID282834, Type: Literature]
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12
[SID103176224]
Inhibition of Lasiodiplodia theobromae mycelium growth at 15 mM measured at 28 degC after 4 days [AID1107759, Type: Literature]
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13
[SID103176224]
Partition coefficient (logP) [AID23251, Type: Literature]
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14
[SID103176224]
Partition coefficient (logP) (benzene) [AID23252, Type: Literature]
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15
[SID103176224]
Partition coefficient (logP) (chloroform) [AID23254, Type: Literature]
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16
[SID103176224]
Partition coefficient (logP) (ether) [AID23255, Type: Literature]
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17
[SID103176224]
Partition coefficient (logP) (hexane) [AID23256, Type: Literature]
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18
[SID103176224]
Decrease in Lasiodiplodia theobromae ligninolytic enzyme production assessed as laccase activity using ABTS as substrate at 1 mM measured at 28 degC after 4 days [AID1107741, Type: Literature]
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19
[SID103176224]
Decrease in Lasiodiplodia theobromae ligninolytic enzyme production assessed as pectinase activity using pectin as substrate at 25 mM measured at 28 degC after 4 days [AID1107736, Type: Literature]
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20
[SID103176224]
Inhibition of Lasiodiplodia theobromae mycelium growth measured at 28 degC after 4 days [AID1107760, Type: Literature]
View