NSC630254 (CID 457676) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(5)
 
 
Unspecified(2)
 
 
Top Targets:
GH31 MGAM SI..(4)
 
 
AmyAc Glg deb..(1)
 
 
Glyco hydro 3..(1)
 
 
BioAssay Types:
Literature(7)
 
 
 
BioActivity Types:
IC50(5)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 7    Data Row: 7   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103624144]
IC50 0.38Inhibition of rat intestinal brush border membrane maltase [AID342793, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
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2
[SID103624144]
IC50 0.6Inhibition of rat intestinal brush border membrane isomaltase [AID342795, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
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3
[SID103624144]
IC50 2.6Inhibition of rat intestinal brush border membrane sucrase [AID342797, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
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4
[SID103624144]
IC50 6.1Inhibition of rabbit muscle amylo-1,6-glucosidase [AID342805, Type: Literature]Glycogen debranching enzyme [gi:544379]
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5
[SID103624144]
IC50 18Inhibition of human lysosomal alpha-glucosidase [AID342799, Type: Literature]Lysosomal alpha-glucosidase [gi:317373572]
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6
[SID103624144]
IC50 18Inhibition of human lysosomal alpha-glucosidase [AID342799, Type: Literature]Lysosomal alpha-glucosidase [gi:317373572]
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7
[SID103624144]
IC50 18Inhibition of human lysosomal alpha-glucosidase [AID342799, Type: Literature]Lysosomal alpha-glucosidase [gi:317373572]
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8
[SID103624144]
 Inhibition of human lysosomal beta-glucosidase at 1000 uM [AID342802, Type: Literature]Glucosylceramidase [gi:55584151]
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9
[SID103624144]
 Inhibition of human lysosomal beta-glucosidase at 1000 uM [AID342802, Type: Literature]Glucosylceramidase [gi:55584151]
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10
[SID103624144]
 Inhibition of rabbit glycogen phosphorylase B at 400 uM [AID342804, Type: Literature]
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