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GNF-Pf-4671 (CID 45488547) - Compound BioActivity Data
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BioActivity Outcomes:
Active(3)
 
 
Inactive(1)
 
 
Unspecified(2)
 
 
BioAssay Types:
Literature(1)
 
 
BioActivity Types:
EC50(2)
 
 
IC50(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 6    Data Row: 6   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103711187]
EC50 0.1186NOVARTIS: Inhibition of Plasmodium falciparum 3D7 (drug-susceptible) proliferation in erythrocyte-based infection assay [AID449703, Type: other]
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2
[SID103711187]
EC50 0.1388NOVARTIS: Inhibition of Plasmodium falciparum W2 (drug-resistant) proliferation in erythrocyte-based infection assay [AID449704, Type: other]
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3
[SID103711187]
CC50 37.92NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7) [AID449705, Type: other]
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4
[SID103711187]
NOVARTIS: Inhibition Frequency Index (IFI) - the number of HTS assays where a compound showed > 50% inhibition/induction, expressed as a percentage of the number of assays in which the compound was tested. [AID449706, Type: other]
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5
[SID103711187]
NOVARTIS: Antimalarial liver stage activity measured as a greater than 50% reduction in Plasmodium yoelii schizont area in HepG2-A16-CD81 cells at 10uM compound concentration, determined by immuno-fluorescence. [AID602118, Type: other]
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6
[SID131335427]
IC50 Novartis GNF Liver Stage Dataset: Malariabox Annotation [AID602156, Type: Literature]
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