SureCN161992 (CID 45487448) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(1)
 
 
Unspecified(5)
 
 
Top Targets:
7TM GPCR Srsx(2)
 
 
7TM GPCR Srx(1)
 
 
BioAssay Types:
Literature(6)
 
 
 
BioActivity Types:
IC50(4)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 6    Data Row: 6   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103707925]
IC50 0.00013Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation counting [AID447594, Type: Literature]Neuropeptide Y receptor type 1 [gi:128997]
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2
[SID103707925]
IC50 0.00013Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation counting [AID447594, Type: Literature]Neuropeptide Y receptor type 1 [gi:128997]
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3
[SID103707925]
IC50 10Displacement of [125I]-PYY from human NPYY2 receptor [AID447596, Type: Literature]Neuropeptide Y receptor type 2 [gi:1352610]
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4
[SID103707925]
IC50 10Displacement of [125I]-PYY from human NPYY2 receptor [AID447596, Type: Literature]Neuropeptide Y receptor type 2 [gi:1352610]
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5
[SID103707925]
IC50 10Displacement of [125I]-PYY from human NPYY5 receptor [AID447598, Type: Literature]Neuropeptide Y receptor type 5 [gi:215274093]
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6
[SID103707925]
IC50 10Displacement of [125I]-PYY from human NPYY4 receptor [AID447597, Type: Literature]Neuropeptide Y receptor type 4 [gi:1709423]
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7
[SID103707925]
 Ratio of permeability from basal to apical side to apical to basal side of human KB-3-1 cells by scintillation counting [AID447595, Type: Literature]
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8
[SID103707925]
 Octanol-water distribution coefficient log Dat pH 7.4 by water-plug aspiration/injection method combined with HPLC-mass spectrometry [AID447593, Type: Literature]
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