CHEMBL579203 (CID 45484408) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(4)
 
 
Unspecified(2)
 
 
Top Targets:
prostaglandin..(2)
 
 
Cyt c Oxidase..(1)
 
 
BioAssay Types:
Literature(6)
 
 
 
BioActivity Types:
IC50(4)
 
 
SAR
Target summary
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 6    Data Row: 6   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103701713]
IC50 0.091Inhibition of sheep COX2 [AID514961, Type: Literature]
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2
[SID103701713]
IC50 0.091Inhibition of ovine COX2 by chemiluminescent enzyme assay [AID448078, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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3
[SID103701713]
IC50 13.4Inhibition of ovine COX1 by chemiluminescent enzyme assay [AID448077, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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4
[SID103701713]
IC50 13.4Inhibition of sheep COX1 [AID514960, Type: Literature]Cytochrome c oxidase subunit 1 [gi:5921840]
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5
[SID103701713]
 Selectivity index, ratio of IC50 for ovine COX1 to IC50 for ovine COX2 [AID448079, Type: Literature]
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6
[SID103701713]
 Selectivity index, ratio of IC50 for sheep COX1 to IC50 for COX2 [AID514962, Type: Literature]
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