Bookmark and Share
AGN-PC-07CMWA (CID 45479888) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(71)
 
 
Inactive(259)
 
 
Inconclusive(22)
 
 
Unspecified(11)
 
 
Top Targets:
7TM GPCR Srx(12)
 
 
7TM GPCR Srsx(11)
 
 
PP1c bdg(9)
 
 
 
 
ABCC CFTR1(9)
 
 
 
 
Troponin(6)
 
 
 
BioAssay Types:
Screening(245)
 
 
 
 
Confirmatory(106)
 
 
 
 
 
Literature(9)
 
 
BioActivity Types:
Potency(75)
 
 
 
 
 
IC50(30)
 
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 303    Data Row: 363   Total Pages: 19   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID93576953]
Potency 0.0231qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
2
[SID93576953]
Potency 0.0326qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
3
[SID93576953]
Potency 0.4109Nrf2 qHTS screen for inhibitors: Nrf2 A549 ARE-Fluc Confirmation Assay for Hit Validation [AID720524, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
View
4
[SID93576953]
Potency 0.6513qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
View
5
[SID93576953]
Potency 0.7308qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
View
6
[SID93576953]
Potency 2.3109Nrf2 qHTS screen for inhibitors [AID504444, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
View
7
[SID93576953]
IC50_Mean 3Dose Response confirmation of uHTS small molecule hits for cystic fibrosis induced NFkb Inhibitors in a PAF-induced IL8 counterscreen [AID624343, Type: confirmatory]interleukin-8 precursor [Homo sapiens] [gi:10834978]
View
8
[SID93576953]
IC50_1_GAPDH 6hr 3.095Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in screening - selectivity counter screen assays - Set 2 [AID651549_1, Type: confirmatory]Glyceraldehyde-3-phosphate dehydrogenase [gi:120649]
View
9
[SID93576953]
IC50_1_PEG-3 6hr 3.104Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in screening - selectivity counter screen assays - Set 2 [AID651549_3, Type: confirmatory]protein phosphatase 1 regulatory subunit 15A [Rattus norvegicus] [gi:78486550]
View
10
[SID93576953]
IC50 3.404Counterscreen for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3):Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) [AID624395, Type: confirmatory]transactivating tegument protein VP16 [Human herpesvirus 1] [gi:9629429]
View
11
[SID93576953]
IC50 4.207Luminescence-based cell-based high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) [AID624394, Type: confirmatory]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
View
12
[SID93576953]
IC50_1_GAPDH 24hr 4.36Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in screening - selectivity counter screen assays - Set 2 [AID651549_2, Type: confirmatory]Glyceraldehyde-3-phosphate dehydrogenase [gi:120649]
View
13
[SID93576953]
IC50_1_PEG-3 24hr 9.307Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in screening - selectivity counter screen assays - Set 2 [AID651549_4, Type: confirmatory]protein phosphatase 1 regulatory subunit 15A [Rattus norvegicus] [gi:78486550]
View
14
[SID93576953]
Potency 11.9173qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]serine/threonine-protein kinase PLK1 [Homo sapiens] [gi:21359873]
View
15
[SID93576953]
Potency 17.7828qHTS for Inhibitors of Polymerase Eta [AID588591, Type: confirmatory]DNA polymerase eta [Homo sapiens] [gi:5729982]
View
16
[SID93576953]
Potency 22.3872qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
View
17
[SID93576953]
Potency 75.6863qHTS for Inhibitors of Polymerase Eta: Confirmatory Assay for Cherry-picked Compounds [AID720502, Type: confirmatory]DNA polymerase eta [Homo sapiens] [gi:5729982]
View
18
[SID93576953]
Luminescence-based cell-based high throughput confirmation assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) [AID624378, Type: screening]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
View
19
[SID93576953]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of Escherichia coli DNA-binding ATP-dependent protease La (eLon) [AID602123, Type: screening]DNA-binding ATP-dependent protease La [Escherichia coli str. K-12 substr. MG1655] [gi:16128424]
View
20
[SID93576953]
Fluorescence polarization-based biochemical high throughput confirmation assay for inhibitors of Escherichia coli DNA-binding ATP-dependent protease La (eLon) [AID602230, Type: screening]DNA-binding ATP-dependent protease La [Escherichia coli str. K-12 substr. MG1655] [gi:16128424]
View