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BioActivity Data for Compound LORECLEZOLE HYDROCHLORIDE (CID 45073437)

BioActivity Outcomes:
Active(1)
 
 
Inactive(89)
 
 
Inconclusive(15)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
 
NR LBD ER(7)
 
 
NR LBD Fxr(4)
 
 
NR LBD GR(4)
 
 
BioAssay Types:
Confirmatory(71)
 
 
 
Summary(24)
 
 
 
 
Screening(10)
 
 
BioAssay Categories:
Toxicity(6)
 
 
Cell-based(8)
 
 
BioActivity Types:
Potency(86)
 
 
 
AC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 105    Data Row: 105   Total Pages: 6   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144204497]
qHTS assay to identify aromatase inhibitors: Summary [AID743139, Type: summary]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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2
[SID170466636]
Ac50 1.41254qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, green channel [AID1117310, Type: confirmatory]
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3
[SID144204497]
Potency-Replicate_1 26.8325qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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4
[SID170466636]
Ac50 39.8107qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen2, ratio channel [AID1117312, Type: confirmatory]
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5
[SID170466636]
Ac50 39.8107qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, blue channel [AID1117314, Type: confirmatory]
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6
[SID170466636]
nuclear beta catenin stimulation in WNT3A conditioned C2C12 cells-screen [AID1117326, Type: screening]
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7
[SID170466636]
insulin secretion from INS-1E cells in the presence of 5 mM glucose-screen [AID1117329, Type: screening]
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8
[SID170466636]
GSK3B-pretreated HCT116 viability from Cell TiterGlo-screen [AID1117336, Type: screening]
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9
[SID170466636]
VEGF stimulated ADSC/ECFC co-culture CD31-stained tube area decrease-screen [AID1117340, Type: screening]
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10
[SID170466636]
GLP1 secretion from NCI-H716 cells-screen [AID1117341, Type: screening]
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11
[SID170466636]
HCT116 viability from Cell TiterGlo-screen [AID1117342, Type: screening]
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12
[SID170466636]
SW480 viability from Cell TiterGlo-screen [AID1117343, Type: screening]
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13
[SID170466636]
DLD-1 viability from Cell TiterGlo-screen [AID1117346, Type: screening]
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14
[SID144204497]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway - cell viability counter screen [AID720693, Type: confirmatory]
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15
[SID170466636]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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16
[SID170466636]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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17
[SID170466636]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
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18
[SID170466636]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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19
[SID170466636]
Potency-Replicate_1 qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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20
[SID170466636]
Potency-Replicate_1 qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen [AID743209, Type: confirmatory]
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