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BioActivity Data for Compound LORECLEZOLE HYDROCHLORIDE (CID 45073437)

BioActivity Outcomes:
Active(2)
 
 
Inactive(105)
 
 
Inconclusive(17)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
 
NR LBD ER(7)
 
 
NR LBD Fxr(4)
 
 
NR LBD GR(4)
 
 
BioAssay Types:
Confirmatory(85)
 
 
 
Summary(29)
 
 
 
 
Screening(10)
 
 
BioAssay Categories:
Toxicity(6)
 
 
Cell-based(8)
 
 
BioActivity Types:
Potency(102)
 
 
 
 
AC50(6)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 124    Data Row: 124   Total Pages: 7   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID170466636]
Ratio Potency (uM) 9.52052qHTS assay to identify small molecule agonists of the AP-1 signaling pathway: Summary [AID1159528, Type: summary]v-jun sarcoma virus 17 oncogene homolog (avian) [Homo sapiens] [gi:119627033]
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2
[SID144204497]
qHTS assay to identify aromatase inhibitors: Summary [AID743139, Type: summary]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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3
[SID170466636]
AC50 (uM) 1.4125qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 green channel [AID1117298, Type: confirmatory]
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4
[SID170466636]
Ac50 1.41254qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, green channel [AID1117310, Type: confirmatory]
View
5
[SID144204497]
Potency-Replicate_1 26.8325qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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6
[SID170466636]
Ac50 39.8107qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen2, ratio channel [AID1117312, Type: confirmatory]
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7
[SID170466636]
Ac50 39.8107qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, blue channel [AID1117314, Type: confirmatory]
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8
[SID170466636]
AC50 (uM) 39.8107qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 blue channel [AID1117304, Type: confirmatory]
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9
[SID170466636]
AC50 (uM) 39.8107qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 ratio channel [AID1117305, Type: confirmatory]
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10
[SID144204497]
Potency-Replicate_1 qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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11
[SID144204497]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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12
[SID144204497]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HepG2 cells [AID720675, Type: confirmatory]
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13
[SID144204497]
Potency-Replicate_1 qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
View
14
[SID144204497]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway - cell viability counter screen [AID743074, Type: confirmatory]
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15
[SID170466636]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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16
[SID144204497]
Potency-Replicate_1 qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway - cell viability counter screen [AID743086, Type: confirmatory]
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17
[SID144204497]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line - cell viability counter screen [AID743081, Type: confirmatory]
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18
[SID170466636]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID1159521, Type: confirmatory]RAR-related orphan receptor gamma [Mus musculus] [gi:15928672]
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19
[SID170466636]
Antagonist Potency (uM) qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway: Summary [AID1159523, Type: summary]RAR-related orphan receptor gamma [Mus musculus] [gi:15928672]
View
20
[SID170466636]
Ratio Potency (uM) qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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