NCGC00188743-01
(CID
44887548
) -
BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(
2
)
Inactive(
1
)
Top Targets:
JmjC(
2
)
PFDH like(
1
)
BioAssay Types:
Confirmatory(
3
)
BioActivity Types:
Potency(
3
)
SAR
Target summary
Data download
Chemical Probe
Active
Inactive
Inconclusive
Unspecified
Total Bioassays: 3 Data Row: 3 Total Pages: 1
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#
Substance
Activity
BioAssay
Target
Links
Outcome
Type
Value [μM]
1
[SID
90419382
]
Active
Potency
20.434
Confirmation qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E) [AID
2677
, Type: confirmatory]
Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:
221046486
]
View
X
Row No.
1
Structure
Substance
SID
90419382
CID
44887548
Outcome
Active
Potency
20.434 [uM]
BioAssay
Confirmation qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E)
AID
2677
BioAssay type
confirmatory
Target
Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:
221046486
]
PubMed
Data Table
2
[SID
90419382
]
Active
Potency
32.3857
Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E): 8HQs - Round 1 [AID
493212
, Type: confirmatory]
Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:
221046486
]
View
X
Row No.
2
Structure
Substance
SID
90419382
CID
44887548
Outcome
Active
Potency
32.3857 [uM]
BioAssay
Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E): 8HQs - Round 1
AID
493212
BioAssay type
confirmatory
Target
Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:
221046486
]
PubMed
Data Table
3
[SID
90419382
]
Inactive
Potency
Counterscreen for JMJD2E Inhibitors: qHTS Assay for Inhibitors of Formaldehyde Dehydrogenase (FDH) [AID
2680
, Type: confirmatory]
formaldehyde dehydrogenase [Pseudomonas putida] [gi:
416247
]
View
X
Row No.
3
Structure
Substance
SID
90419382
CID
44887548
Outcome
Inactive
Potency
[uM]
BioAssay
Counterscreen for JMJD2E Inhibitors: qHTS Assay for Inhibitors of Formaldehyde Dehydrogenase (FDH)
AID
2680
BioAssay type
confirmatory
Target
formaldehyde dehydrogenase [Pseudomonas putida] [gi:
416247
]
PubMed
Data Table