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[4-[(2-hydroxybenzoyl)diazenyl]anilino] 4-methylbenzoate (CID 4483669) - Compound BioActivity Data
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BioActivity Outcomes:
Active(38)
 
 
Inactive(698)
 
 
Inconclusive(23)
 
 
Unspecified(2)
 
 
Top Targets:
7tm 4(43)
 
 
 
alkPPc(12)
 
 
Bcl-2 like(11)
 
 
 
Tryp SPc(9)
 
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(523)
 
 
 
 
 
Confirmatory(214)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(148)
 
 
 
 
 
IC50(48)
 
 
 
EC50(10)
 
 
AC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 692    Data Row: 761   Total Pages: 39   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID14732345]
AC50_uM 1.515Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Cancer Stem Cells [AID449748, Type: confirmatory]
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2
[SID14732345]
Potency 2.2387qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding [AID1460, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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3
[SID14732345]
AC50_uM 3.557Dose Response HTS Screen to Identify Cytotoxic Compounds of HMLE_sh_eGFP [AID463074, Type: confirmatory]
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4
[SID14732345]
Absolute IC50 4.35Dose Response Confirmation for Small Molecule Inhibitors of Epstein-Barr Virus [AID1419, Type: confirmatory]BZLF2 [Human herpesvirus 4 type 2] [gi:139424501]
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5
[SID14732345]
IC50 8.20371Estrogen Receptor-beta Coactivator Binding Inhibitors Dose Response Confirmation [AID733, Type: confirmatory]estrogen receptor beta isoform 1 [Homo sapiens] [gi:10835013]
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6
[SID14732345]
IC50 8.43821Estrogen Receptor-alpha Coactivator Binding Inhibitors Dose Response Confirmation [AID713, Type: confirmatory]Estrogen receptor 1 [Homo sapiens] [gi:118764400]
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7
[SID14732345]
Potency 8.9125qHTS for Inhibitors of Polymerase Eta [AID588591, Type: confirmatory]DNA polymerase eta isoform 1 [Homo sapiens] [gi:5729982]
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8
[SID14732345]
IC50 11.413High Throughput Fluorescence Polarization Screen for Bcl-B Phenotype Converters [AID748, Type: confirmatory]nuclear receptor subfamily 4 group A member 1 isoform 1 [Homo sapiens] [gi:27894344]
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9
[SID14732345]
Potency 11.9955qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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10
[SID14732345]
IC50 12.4TR-FRET secondary assay for HTS discovery of chemical inhibitors of Hsp70 [AID786, Type: confirmatory]heat shock 70kDa protein 1A [Homo sapiens] [gi:123271505]
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11
[SID14732345]
Potency 12.9953qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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12
[SID14732345]
Potency 16.3601qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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13
[SID14732345]
Potency 17.7828VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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14
[SID14732345]
IC50 25.2High Throughput Screening Assay for Hsp70 Inhibitors [AID583, Type: confirmatory]heat shock 70kDa protein 1A [Homo sapiens] [gi:123271505]
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15
[SID14732345]
Potency 28.1838qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase) [AID894, Type: confirmatory]15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 [Homo sapiens] [gi:31542939]
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16
[SID14732345]
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID743269, Type: screening]integrase, partial [Human immunodeficiency virus 1] [gi:2853980]
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17
[SID14732345]
Colorimetric Assay for Inhibitors for NALP1 [AID2071, Type: screening]NACHT, LRR and PYD domains-containing protein 1 isoform 1 [Homo sapiens] [gi:14719829]
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18
[SID14732345]
CYP2C9 Assay [AID777, Type: screening]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
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19
[SID14732345]
uHTS of Mcl-1/Bid interaction inhibitors [AID1021, Type: screening]Mcl-1 [Homo sapiens] [gi:7582271]
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20
[SID14732345]
uHTS of Mcl-1/Noxa interaction inhibitors [AID1022, Type: screening]Mcl-1 [Homo sapiens] [gi:7582271]
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