Bookmark and Share
CHEMBL2180814 (CID 44825297) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(10)
 
 
Inactive(167)
 
 
Unspecified(3)
 
 
Top Targets:
7TM GPCR Srx(7)
 
 
GH31 MGAM SI..(6)
 
 
7TM GPCR Srsx(4)
 
 
RasGEF(4)
 
 
NR DBD CAR(3)
 
 
BioAssay Types:
Screening(138)
 
 
Confirmatory(26)
 
 
 
Literature(15)
 
 
 
 
BioActivity Types:
Potency(26)
 
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 166    Data Row: 180   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID163318268]
IC50 1.88Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assay [AID705434, Type: Literature]
View
2
[SID89650112]
Potency 1.8818Confirmation of Inhibitors and Activators of Purified Human alpha-Glucosidase [AID2115, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
View
3
[SID89650112]
Potency 2.3691Confirmation of Inhibitors and Activators of Purified Human alpha-Glucosidase Using an Alternate Red Fluorescent Susbtrate [AID2110, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
View
4
[SID163318268]
IC50 2.37Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assay [AID705433, Type: Literature]
View
5
[SID89650112]
Potency 6.6769Confirmation of Inhibitors and Activators of Human alpha-Glucosidase From Spleen Homogenate [AID2113, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
View
6
[SID89650112]
Potency 6.7066qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen [AID2100, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
View
7
[SID89650112]
Potency 11.8734Confirmation of Inhibitors and Activators of Human alpha-Glucosidase From Spleen Homogenate Using an Alternate Red Fluorescent Susbtrate [AID2111, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
View
8
[SID89650112]
Potency 125.893qHTS Assay for Inhibitors of JMJD2A-Tudor Domain [AID504339, Type: confirmatory]Chain A, Jmjd2a Tandem Tudor Domains In Complex With A Trimethylated Histone H4-K20 Peptide [gi:162330054]
View
9
[SID163318268]
Aqueous solubility in PBS buffer [AID705415, Type: Literature]
View
10
[SID89650112]
qHTS Assay for Inhibitors of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease: Stabilizers of Alpha-Glucosidase Under Thermal Denaturation Conditions [AID2641, Type: other]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
View
11
[SID163318268]
Permeability from basolateral to apical side of human Caco2 cells [AID705412, Type: Literature]
View
12
[SID163318268]
Permeability from apical to basolateral side of human Caco2 cells [AID705413, Type: Literature]
View
13
[SID163318268]
Half life in mouse liver microsomes [AID705414, Type: Literature]
View
14
[SID99495642]
Counterscreen of compound fluorescence effects on High-throughput multiplex microsphere screening for inhibitors of toxin protease [AID624483, Type: screening]
View
15
[SID99495642]
uHTS identification of small molecule Triacylglycerol inhbitors in a fluoresence assay [AID651582, Type: screening]
View
16
[SID99495642]
HIV entry: Env-mediated Cell Fusion Measured in Cell-Based System Using Plate Reader - 7013-01_Inhibitor_SinglePoint_HTS_Activity [AID651610, Type: screening]
View
17
[SID99495642]
DENV2 CPE-Based HTS Measured in Cell-Based and Microorganism Combination System Using Plate Reader - 2149-01_Other_SinglePoint_HTS_Activity [AID651640, Type: screening]
View
18
[SID99495642]
HTS for the detection of C. neoformans cell lysis via adenylate kinase (AK) release Measured in Microorganism System Using Plate Reader - 2162-01_Inhibitor_SinglePoint_HTS_Activity [AID651654, Type: screening]
View
19
[SID99495642]
Luminescence Cell-Based Primary HTS to identify inhibitors of the oncoprotein EWS/Fli transcriptional activity Measured in Cell-Based System Using Plate Reader - 7014-01_Inhibitor_SinglePoint_HTS_Activity [AID651661, Type: screening]
View
20
[SID99495642]
Flow Cytometric HTS Screening for Inhibitors of Lytic Granule Exocytosis with MLPCN Compound Library [AID651702, Type: screening]
View