Bookmark and Share

BioActivity Data for Compound CHEMBL2180814 (CID 44825297)

BioActivity Outcomes:
Active(10)
 
 
Inactive(168)
 
 
Unspecified(3)
 
 
Top Targets:
7tm 4(11)
 
 
GH31 MGAM SI..(6)
 
 
RasGEF(4)
 
 
Toxin trans(3)
 
 
NR DBD CAR(3)
 
 
BioAssay Types:
Screening(138)
 
 
Confirmatory(27)
 
 
 
Literature(15)
 
 
 
 
BioAssay Categories:
In vitro(1)
 
 
Biochemical(49)
 
 
 
Toxicity(3)
 
 
ADME(3)
 
 
Cell-based(56)
 
 
 
Organism-base..(5)
 
 
BioActivity Types:
Potency(27)
 
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 167    Data Row: 181   Total Pages: 10   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID163318268]
IC50 1.88Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assay [AID705434, Type: Literature]
View
2
[SID89650112]
Potency 1.8818Confirmation of Inhibitors and Activators of Purified Human alpha-Glucosidase [AID2115, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
View
3
[SID89650112]
Potency 2.3691Confirmation of Inhibitors and Activators of Purified Human alpha-Glucosidase Using an Alternate Red Fluorescent Susbtrate [AID2110, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
View
4
[SID163318268]
IC50 2.37Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assay [AID705433, Type: Literature]
View
5
[SID89650112]
Potency 6.6769Confirmation of Inhibitors and Activators of Human alpha-Glucosidase From Spleen Homogenate [AID2113, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
View
6
[SID89650112]
Potency 6.7066qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen [AID2100, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
View
7
[SID89650112]
Potency 11.8734Confirmation of Inhibitors and Activators of Human alpha-Glucosidase From Spleen Homogenate Using an Alternate Red Fluorescent Susbtrate [AID2111, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
View
8
[SID89650112]
Potency 125.893qHTS Assay for Inhibitors of JMJD2A-Tudor Domain [AID504339, Type: confirmatory]Chain A, Jmjd2a Tandem Tudor Domains In Complex With A Trimethylated Histone H4-K20 Peptide [gi:162330054]
View
9
[SID163318268]
Aqueous solubility in PBS buffer [AID705415, Type: Literature]
View
10
[SID89650112]
qHTS Assay for Inhibitors of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease: Stabilizers of Alpha-Glucosidase Under Thermal Denaturation Conditions [AID2641, Type: other]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
View
11
[SID163318268]
Permeability from apical to basolateral side of human Caco2 cells [AID705413, Type: Literature]
View
12
[SID163318268]
Half life in mouse liver microsomes [AID705414, Type: Literature]
View
13
[SID163318268]
Permeability from basolateral to apical side of human Caco2 cells [AID705412, Type: Literature]
View
14
[SID99495642]
Wnt/Beta-catenin HTS Measured in Cell-Based System Using Plate Reader - 2161-01_Activator_SinglePoint_HTS_Activity [AID743398, Type: screening]
View
15
[SID99495642]
High Content Cell-Based Imaging Primary HTS to Identify Small Molecules Involved in X-Chromosome Reactivation and Reprogramming Measured in Cell-Based System Using Imaging - 7015-01_Activator_SinglePoint_HTS_Activity_Set2 [AID743238, Type: screening]
View
16
[SID99495642]
Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition [AID720647, Type: screening]
View
17
[SID99495642]
Inhibition of Alexa 488-Fibronectin deposition #on AH1F cell monolayers Measured in Cell-Based System Using Plate Reader - 7059-01_Inhibitor_SinglePoint_HTS_Activity [AID743247, Type: screening]
View
18
[SID99495642]
Luminescent GLuc Reporter Gene Assay Primary HTS to Identify Small Molecule Activator of Glucose Dependent Insulin Secretion Measured in Cell-Based System Using Plate Reader - 7055-01_Activator_SinglePoint_HTS_Activity [AID743287, Type: screening]
View
19
[SID99495642]
Potency High Throughput Screening for Foot and Mouth Disease Virus Antivirals [AID1159524, Type: confirmatory]
View
20
[SID99495642]
HTS for Bacterial rRNA inhibitors Measured in Microorganism-Based System Using Plate Reader - 7056-01_Inhibitor_SinglePoint_HTS_Activity [AID720706, Type: screening]
View