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BioActivity Data for Compound Niclosamide (CID 4477)

BioActivity Outcomes:
Active(343)
 
 
Inactive(819)
 
 
Inconclusive(274)
 
 
Unspecified(87)
 
 
Top Targets:
7tm 4(45)
 
 
 
 
p450(24)
 
 
 
 
NR LBD PPAR(21)
 
 
 
NR LBD ER(17)
 
 
 
 
NR LBD AR(16)
 
 
 
BioAssay Types:
Confirmatory(741)
 
 
 
 
 
Screening(374)
 
 
 
 
Literature(267)
 
 
 
 
 
Summary(53)
 
 
 
 
BioAssay Categories:
In vitro(2)
 
 
 
In vivo(5)
 
 
 
Biochemical(160)
 
 
 
 
Toxicity(55)
 
 
 
 
 
ADME(6)
 
 
 
Cell-based(252)
 
 
 
 
 
Organism-base..(10)
 
 
 
BioActivity Types:
Potency(674)
 
 
 
 
 
IC50(98)
 
 
 
 
 
AC50(16)
 
 
 
EC50(4)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1054    Data Row: 1523   Total Pages: 77   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103516894]
IC50 0.00056Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay [AID524796, Type: Literature]
View
2
[SID103516894]
IC50 0.00074Antiplasmodial activity against Plasmodium falciparum GB4 after 72 hrs by SYBR green assay [AID524794, Type: Literature]
View
3
[SID103516894]
IC50 0.00089Antiplasmodial activity against Plasmodium falciparum HB3 after 72 hrs by SYBR green assay [AID524795, Type: Literature]
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4
[SID103516894]
IC50 0.00089Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green assay [AID524790, Type: Literature]
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5
[SID103516894]
IC50 0.00089Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay [AID524791, Type: Literature]
View
6
[SID103516894]
IC50 0.001Antiplasmodial activity against Plasmodium falciparum D10 after 72 hrs by SYBR green assay [AID524792, Type: Literature]
View
7
[SID170465184]
IC50 0.001RKO viability from Cell TiterGlo-IC50 [AID1117322, Type: confirmatory]
View
8
[SID170465184]
IC50 0.001SW480 viability from Cell TiterGlo-IC50 [AID1117338, Type: confirmatory]
View
9
[SID170465184]
IC50 0.00144HCT116 viability from Cell TiterGlo-IC50 [AID1117332, Type: confirmatory]
View
10
[SID103516894]
IC50 0.00148Antiplasmodial activity against Plasmodium falciparum Dd2 after 72 hrs by SYBR green assay [AID524793, Type: Literature]
View
11
[SID170465184]
IC50 0.00295GSK3B-pretreated HCT116 viability from Cell TiterGlo-IC50 [AID1117339, Type: confirmatory]
View
12
[SID170465184]
IC50 0.00349DLD-1 viability from Cell TiterGlo-IC50 [AID1117352, Type: confirmatory]
View
13
[SID170465184]
IC50 0.00826Colo320 viability from Cell TiterGlo-IC50 [AID1117334, Type: confirmatory]
View
14
[SID144211066]
Potency-Replicate_1 0.0097qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
View
15
[SID144203760]
Potency-Replicate_1 0.0266qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
View
16
[SID144203760]
Ratio Potency (uM) 0.0348017qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
View
17
[SID56463356]
Potency 0.0398qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory]Niemann-Pick C1 protein precursor [Homo sapiens] [gi:255652944]
View
18
[SID90341111]
Potency 0.0651qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory]Niemann-Pick C1 protein precursor [Homo sapiens] [gi:255652944]
View
19
[SID144203760]
Potency-Replicate_1 0.075qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 [AID651632, Type: confirmatory]ATPase family AAA domain-containing protein 5 [gi:296439460]
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20
[SID144203760]
Potency-Replicate_1 0.0944qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
View