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Niclosamide (CID 4477) - Compound BioActivity Data
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BioActivity Outcomes:
Active(318)
 
 
Inactive(794)
 
 
Inconclusive(267)
 
 
Unspecified(84)
 
 
Top Targets:
7TM GPCR Srx(26)
 
 
 
 
p450(24)
 
 
 
 
NR LBD PPAR(21)
 
 
 
7TM GPCR Srsx(18)
 
 
NR LBD ER(17)
 
 
 
 
BioAssay Types:
Confirmatory(734)
 
 
 
 
 
Screening(361)
 
 
 
 
Literature(185)
 
 
 
 
 
Summary(49)
 
 
 
 
BioActivity Types:
Potency(658)
 
 
 
 
 
IC50(81)
 
 
 
 
 
AC50(6)
 
 
 
EC50(4)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1002    Data Row: 1463   Total Pages: 74   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103516894]
IC50 0.00056Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay [AID524796, Type: Literature]
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2
[SID103516894]
IC50 0.00074Antiplasmodial activity against Plasmodium falciparum GB4 after 72 hrs by SYBR green assay [AID524794, Type: Literature]
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3
[SID103516894]
IC50 0.00089Antiplasmodial activity against Plasmodium falciparum HB3 after 72 hrs by SYBR green assay [AID524795, Type: Literature]
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4
[SID103516894]
IC50 0.00089Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green assay [AID524790, Type: Literature]
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5
[SID103516894]
IC50 0.00089Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay [AID524791, Type: Literature]
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6
[SID103516894]
IC50 0.001Antiplasmodial activity against Plasmodium falciparum D10 after 72 hrs by SYBR green assay [AID524792, Type: Literature]
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7
[SID103516894]
IC50 0.00148Antiplasmodial activity against Plasmodium falciparum Dd2 after 72 hrs by SYBR green assay [AID524793, Type: Literature]
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8
[SID144211066]
Potency-Replicate_1 0.0097qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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9
[SID144203760]
Potency-Replicate_1 0.0266qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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10
[SID144203760]
Ratio Potency (uM) 0.0348017qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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11
[SID56463356]
Potency 0.0398qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory]Niemann-Pick C1 protein precursor [Homo sapiens] [gi:255652944]
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12
[SID90341111]
Potency 0.0651qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory]Niemann-Pick C1 protein precursor [Homo sapiens] [gi:255652944]
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13
[SID144203760]
Potency-Replicate_1 0.075qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 [AID651632, Type: confirmatory]ATPase family AAA domain-containing protein 5 [gi:296439460]
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14
[SID144203760]
Potency-Replicate_1 0.0944qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
View
15
[SID144211066]
Potency-Replicate_1 0.0969qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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16
[SID103516894]
EC50 0.1Antiviral activity against SARS coronavirus in Vero E6 cells assessed as inhibition of viral replication by ELISA [AID297149, Type: Literature]
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17
[SID90341111]
Potency 0.1qHTS Assay for Rab9 Promoter Activators [AID485297, Type: confirmatory]ras-related protein Rab-9A [Homo sapiens] [gi:4759012]
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18
[SID11111533]
Potency 0.1qHTS Assay for Identification of Small Molecule Agonists for Thrombopoietin (TPO) Signaling Pathway [AID917, Type: confirmatory]Thrombopoietin [Homo sapiens] [gi:120660324]
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19
[SID104171199]
Potency 0.1142Biochemical firefly luciferase enzyme assay for NPC [AID624030, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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20
[SID144211066]
Potency-Replicate_1 0.123qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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