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2-butenal (CID 447466) - Compound BioActivity Data
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BioActivity Outcomes:
Active(3)
 
 
Inactive(154)
 
 
Inconclusive(6)
 
 
Unspecified(1)
 
 
Top Targets:
NR LBD PPAR(5)
 
 
NR LBD TR(4)
 
 
HSD10-like SD..(4)
 
 
NR LBD ROR li..(3)
 
 
P53(3)
 
 
BioAssay Types:
Confirmatory(150)
 
 
 
Literature(3)
 
 
 
BioActivity Types:
Potency(114)
 
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 152    Data Row: 164   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103756899]
EC50 16Activation of TRPA1 channel [AID482142, Type: Literature]
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2
[SID48413490]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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3
[SID48413490]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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4
[SID17389091]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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5
[SID17389091]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_1, Type: other]
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6
[SID17389091]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_2, Type: other]
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7
[SID17389091]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_3, Type: other]
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8
[SID17389091]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_4, Type: other]
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9
[SID17389091]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_5, Type: other]
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10
[SID17389091]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_6, Type: other]
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11
[SID17389091]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_7, Type: other]
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12
[SID17389091]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_8, Type: other]
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13
[SID17389091]
Potency-Replicate_1 qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway - cell viability counter screen [AID720652, Type: confirmatory]
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14
[SID17389091]
Potency-Replicate_1 qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity - cell viability counter screen [AID720653, Type: confirmatory]
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15
[SID17389091]
Potency qHTS assay for cell viability of HEK293 cells [AID743288, Type: confirmatory]
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16
[SID17389091]
Potency qHTS assay for cell viability of the p53RE-bla HCT-116 cell line [AID743292, Type: confirmatory]
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17
[SID17389091]
Potency-Replicate_1 qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity [AID720636, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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18
[SID17389091]
Potency qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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19
[SID17389091]
Potency qHTS Assay for Anthrax Lethal Toxin Internalization [AID912, Type: confirmatory]lethal factor [Bacillus anthracis str. A2012] [gi:21392848]
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20
[SID17389091]
Potency qHTS assay to identify small molecules that stimulate Tumor Necrosis Factor-alpha (TNF-alpha) secretion [AID651757, Type: confirmatory]tumor necrosis factor [Homo sapiens] [gi:25952111]
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