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PD 173955 (CID 447077) - Compound BioActivity Data
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BioActivity Outcomes:
Active(220)
 
 
Inactive(7)
 
 
Unspecified(256)
 
 
Top Targets:
PKc(48)
 
 
 
PKc like(40)
 
 
 
PTKc Abl(17)
 
 
STKc AGC(17)
 
 
 
PTKc EGFR(12)
 
 
 
BioAssay Types:
Literature(476)
 
 
 
Confirmatory(7)
 
 
BioActivity Types:
Kd(444)
 
 
 
IC50(26)
 
 
 
Potency(7)
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 477    Data Row: 483   Total Pages: 25   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103499403]
Ki 0.0002Inhibition of recombinant c-Abl after 30 mins [AID501985, Type: Literature]
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2
[SID103499403]
Kd 0.00052Binding constant for ABL1(M351T)-phosphorylated kinase domain [AID624985, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
3
[SID103499403]
Kd 0.00055Binding constant for ABL1(E255K)-phosphorylated kinase domain [AID624978, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
4
[SID103499403]
Kd 0.00058Binding constant for ABL1-phosphorylated kinase domain [AID624992, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
5
[SID103499403]
Kd 0.00063Binding constant for ABL1(H396P)-non phosphorylated kinase domain [AID624983, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
6
[SID103499403]
Kd 0.00067Binding constant for CSF1R kinase domain [AID624995, Type: Literature]Macrophage colony-stimulating factor 1 receptor [gi:547770]
View
7
[SID103499403]
Kd 0.00069Binding constant for ABL2 kinase domain [AID624993, Type: Literature]Abelson tyrosine-protein kinase 2 [gi:1168268]
View
8
[SID103499403]
Kd 0.00071Binding constant for SRC kinase domain [AID625016, Type: Literature]Proto-oncogene tyrosine-protein kinase Src [gi:125711]
View
9
[SID103499403]
Kd 0.00088Binding constant for ABL1(Y253F)-phosphorylated kinase domain [AID624990, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
10
[SID103499403]
Kd 0.00093Binding constant for ABL1(Q252H)-phosphorylated kinase domain [AID624987, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
11
[SID103499403]
Kd 0.0011Binding constant for LCK kinase domain [AID625013, Type: Literature]Tyrosine-protein kinase Lck [gi:125474]
View
12
[SID103499403]
Kd 0.0013Binding constant for ABL1(Q252H)-non phosphorylated kinase domain [AID624986, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
13
[SID103499403]
Kd 0.0014Binding constant for ABL1(H396P)-phosphorylated kinase domain [AID624984, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
14
[SID103499403]
Kd 0.0014Binding constant for PDGFRB kinase domain [AID624875, Type: Literature]Platelet-derived growth factor receptor beta [gi:129890]
View
15
[SID103499403]
Kd 0.0015Binding constant for ABL1-non phosphorylated kinase domain [AID624991, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
16
[SID103499403]
Kd 0.0015Binding constant for BLK kinase domain [AID624841, Type: Literature]Tyrosine-protein kinase Blk [gi:158936749]
View
17
[SID103499403]
Kd 0.0016Binding constant for KIT(V559D) kinase domain [AID624791, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
18
[SID103499403]
Kd 0.0018Binding constant for KIT kinase domain [AID624786, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
19
[SID103499403]
IC50 0.002Inhibition of Bcr-Abl fusion protein [AID271012, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
20
[SID103499403]
Kd 0.002Binding constant for EPHB6 kinase domain [AID624957, Type: Literature]Ephrin type-B receptor 6 [gi:294862532]
View