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Mycophenolic Acid (CID 446541) - Compound BioActivity Data
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BioActivity Outcomes:
Active(286)
 
 
Inactive(902)
 
 
Inconclusive(122)
 
 
Unspecified(270)
 
 
Top Targets:
7TM GPCR Srx(31)
 
 
 
p450(31)
 
 
 
 
 
7TM GPCR Srsx(28)
 
 
 
IMPDH(24)
 
 
 
PLDc mTdp1 2(16)
 
 
 
BioAssay Types:
Confirmatory(738)
 
 
 
 
 
Screening(367)
 
 
 
 
Literature(323)
 
 
 
 
 
Summary(24)
 
 
 
 
BioActivity Types:
Potency(463)
 
 
 
 
 
IC50(205)
 
 
 
 
EC50(28)
 
 
 
 
Ki(17)
 
 
 
Kd(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1148    Data Row: 1580   Total Pages: 79   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103226686]
EC50 6e-05Antiproliferative activity against human PBMC assessed as incorporation of [3H]thymidine after 18 hrs by scintillation counting analysis [AID776766, Type: Literature]
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2
[SID103226686]
Ki 0.006Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II isoform); Range is 6-10 nM [AID92748, Type: Literature]
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3
[SID46392307]
Ki 0.006Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure Of Inosine Monophosphate Dehydrogenase In Complex With Mycophenolic Acid [gi:15826575]
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4
[SID46392307]
Ki 0.006Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Crystal Structure Of Inosine Monophosphate Dehydrogenase In Complex With Mycophenolic Acid [gi:15826575]
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5
[SID103226686]
Ki 0.007Inhibition of human IMPDH type 2 [AID303352, Type: Literature]Inosine-5'-monophosphate dehydrogenase 2 [gi:124419]
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6
[SID103226686]
Ki 0.007Inhibition of human IMPDH2 by Spectrophotometer [AID580126, Type: Literature]Inosine-5'-monophosphate dehydrogenase 2 [gi:124419]
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7
[SID103226686]
Ki 0.007Inhibition of human IMPDH [AID776770, Type: Literature]
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8
[SID103226686]
Ki 0.01Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II) [AID92749, Type: Literature]
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9
[SID103226686]
Ki 0.01Inhibition of human IMPDH 2 [AID304372, Type: Literature]Inosine-5'-monophosphate dehydrogenase 2 [gi:124419]
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10
[SID103226686]
Ki 0.01Inhibition of human IMPDH2 [AID348819, Type: Literature]Inosine-5'-monophosphate dehydrogenase 2 [gi:124419]
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11
[SID103226686]
IC50 0.011Inhibition of human IMPDH2 [AID267726, Type: Literature]Inosine-5'-monophosphate dehydrogenase 2 [gi:124419]
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12
[SID103226686]
IC50 0.012Inhibition of human IMPDH2 expressed in Escherichia coli strain BL21(DE3) after 60 mins [AID538354, Type: Literature]Inosine-5'-monophosphate dehydrogenase 2 [gi:124419]
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13
[SID103226686]
IC50 0.014Inhibition of human inosine-5'-monophosphate dehydrogenase 2 [AID92622, Type: Literature]
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14
[SID103226686]
IC50 0.014Inhibition of human inosine monophosphate dehydrogenase IMPDH II [AID92624, Type: Literature]
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15
[SID103226686]
IC50 0.014Inhibitory activity against inosine monophosphate dehydrogenase IMPDH II [AID92740, Type: Literature]
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16
[SID103226686]
IC50 0.015Inhibition of human Inosine-5'-monophosphate dehydrogenase 2 [AID92741, Type: Literature]
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17
[SID103226686]
IC50 0.015Inhibitory activity tested against inosine-5'-monophosphate dehydrogenase 2 (IMPDH-II) enzyme [AID92742, Type: Literature]
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18
[SID103226686]
IC50 0.015Inhibitory concentration against Inosine-5'-monophosphate dehydrogenase 2 was determined [AID92743, Type: Literature]
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19
[SID103226686]
IC50 0.015In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2. [AID92745, Type: Literature]
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20
[SID103226686]
IC50 0.015Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II) [AID91402, Type: Literature]Inosine-5'-monophosphate dehydrogenase 2 [gi:124419]
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