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BioActivity Data for Compound geranyl diphosphate (CID 445995)

BioActivity Outcomes:
Active(4)
 
 
Inactive(1)
 
 
BioAssay Types:
Literature(3)
 
 
 
Confirmatory(2)
 
 
BioAssay Categories:
Biochemical(3)
 
 
 
BioActivity Types:
Ki(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 5   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103220066]
Km 4.4Compound was tested for apparent Km values of Farnesyl diphosphate (FPP) synthase from Pig liver [AID72656, Type: confirmatory]
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2
[SID103220066]
Km 8.4Compound was tested for apparent Km values of Farnesyl diphosphate synthase from Bacteria [AID72650, Type: confirmatory]
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3
[SID103220066]
Inhibition of Baker's yeast squalene synthetase assessed as incorporation of [1-3H]farnesyl pyrophosphate into squalene at 2 to 6 uM after 2 mins by liquid scintillation spectrometer analysis [AID1145974, Type: Literature]
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4
[SID103220066]
Ki Competitive inhibition of Baker's yeast squalene synthetase using [1-3H]farnesyl pyrophosphate as substrate by Lineweaver-Burk graphic analysis [AID1145973, Type: Literature]
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5
[SID103220066]
Inhibition of Baker's yeast squalene synthetase assessed as incorporation of [1-3H]farnesyl pyrophosphate into squalene up to 20 uM after 2 mins by liquid scintillation spectrometer analysis [AID1145975, Type: Literature]
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