Bookmark and Share
CHEMBL501188 (CID 44586781) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(8)
 
 
Unspecified(2)
 
 
Top Targets:
DEADc(1)
 
 
BioAssay Types:
Literature(10)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 10    Data Row: 10   Total Pages: 1   
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103642506]
Inhibition of HIV1 replication in human MT4 cells assessed as reduction in reverse transcriptase at 25 uM after 8 days by western blotting [AID362395, Type: Literature]
View
2
[SID103642506]
Inhibition of HIV1 replication in human MT4 cells assessed as p24 capsid protein level at 25 uM after 8 days by ELISA [AID362396, Type: Literature]
View
3
[SID103642506]
Antiviral activity against HIV1 transfected in human HeLa cells assessed as reduction of p55 viral protein synthesis at 25 uM [AID362397, Type: Literature]
View
4
[SID103642506]
Antiviral activity against HIV1 transfected in human HeLa cells assessed as reduction of p24 viral protein synthesis at 25 uM [AID362398, Type: Literature]
View
5
[SID103642506]
Inhibition of macrophage tropic HIV1 AD8 replication in monocyte-derived macrophages assessed as reduction in reverse transcriptase at 25 uM after 5 days by Western blotting [AID362399, Type: Literature]
View
6
[SID103642506]
Inhibition of macrophage tropic HIV1 AD8 replication in monocyte-derived macrophages p24 capsid protein level at 25 uM after 5 days by ELISA [AID362400, Type: Literature]
View
7
[SID103642506]
Inhibition of HIV1 replication in human MT4 cells assessed as reduction in reverse transcriptase production at 10 uM [AID362393, Type: Literature]
View
8
[SID103642506]
Inhibition of ATP dependent RNA unwinding activity of human RNA helicase DDX3 [AID362394, Type: Literature]ATP-dependent RNA helicase DDX3X [gi:3023628]
View
9
[SID103642506]
Toxicity in BALB/c mouse assessed as tissue necrosis at 0.2 to 200 uM, ip administered weekly twice for 5 weeks relative to control [AID362401, Type: Literature]
View
10
[SID103642506]
Cytotoxicity against human MT4 cells at 1 to 100 uM after 6 days by colorimetric assay relative to control [AID362402, Type: Literature]
View