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ferulic acid (CID 445858) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(39)
 
 
Inactive(588)
 
 
Inconclusive(9)
 
 
Unspecified(393)
 
 
Top Targets:
7tm 4(58)
 
 
 
p450(10)
 
 
 
CAP ED(6)
 
 
 
Tryp SPc(6)
 
 
 
Esterase lipa..(5)
 
 
BioAssay Types:
Screening(340)
 
 
 
Confirmatory(329)
 
 
 
 
 
Literature(177)
 
 
 
 
 
BioActivity Types:
IC50(151)
 
 
 
 
 
Potency(136)
 
 
 
 
Ki(13)
 
 
EC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 975    Data Row: 1029   Total Pages: 52   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103207410]
Ki 0.00077Displacement of [125I]TZDM from human beta amyloid fibril 1-42 [AID308323, Type: Literature]
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2
[SID103207410]
IC50 0.2Antihemorrhagic activity in ddY mouse assessed as inhibition of Protobothrops flavoviridis venom-induced hemorrhage incubated with compound for 10 mins measured after 24 hrs [AID592088, Type: Literature]
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3
[SID103207410]
Ki 2.4Inhibition of human CA2 by stopped-flow CO2 hydration assay [AID462271, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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4
[SID103207410]
Ki 2.89Inhibition of human CA1 by stopped-flow CO2 hydration assay [AID462270, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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5
[SID103207410]
IC50 3.975DRUGMATRIX: Lipoxygenase 15-LO enzyme inhibition (substrate: Linoleic acid) [AID625146, Type: confirmatory]Arachidonate 15-lipoxygenase [gi:126397]
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6
[SID103207410]
Ki 7.04Inhibition of human CA5A by stopped-flow CO2 hydration assay [AID462274, Type: Literature]Carbonic anhydrase 5A, mitochondrial [gi:461680]
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7
[SID103207410]
Ki 7.41Inhibition of human CA7 by stopped-flow CO2 hydration assay [AID462277, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
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8
[SID103207410]
Ki 8.45Inhibition of human CA6 by stopped-flow CO2 hydration assay [AID462276, Type: Literature]Carbonic anhydrase 6 [gi:116241278]
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9
[SID103207410]
Ki 9.43Inhibition of human CA14 by stopped-flow CO2 hydration assay [AID462281, Type: Literature]Carbonic anhydrase 14 [gi:8928036]
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10
[SID103207410]
Ki 9.78Inhibition of human CA12 by stopped-flow CO2 hydration assay [AID462279, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
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11
[SID103207410]
Ki 9.87Inhibition of human CA9 by stopped-flow CO2 hydration assay [AID462278, Type: Literature]Carbonic anhydrase 9 [gi:83300925]
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12
[SID103207410]
Ki 10.5Inhibition of human CA5B by stopped-flow CO2 hydration assay [AID462275, Type: Literature]Carbonic anhydrase 5B, mitochondrial [gi:8928041]
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13
[SID103207410]
Ki 10.8Inhibition of human CA4 by stopped-flow CO2 hydration assay [AID462273, Type: Literature]Carbonic anhydrase 4 [gi:115465]
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14
[SID103207410]
Ki 11.1Inhibition of human CA3 by stopped-flow CO2 hydration assay [AID462272, Type: Literature]Carbonic anhydrase 3 [gi:134047703]
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15
[SID103207410]
Ki 12.2Inhibition of mouse CA13 by stopped-flow CO2 hydration assay [AID462280, Type: Literature]Carbonic anhydrase 13 [gi:30580372]
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16
[SID47193700]
HTS-Luminescent assay for inhibitors of ALR by detection of hydrogen peroxide production Measured in Biochemical System Using Plate Reader - 2036-02_Inhibitor_SinglePoint_HTS [AID485317, Type: screening]FAD-linked sulfhydryl oxidase ALR [Homo sapiens] [gi:54112432]
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17
[SID103207410]
Antihyperglycemic activity in po dosed diabetic KK-Ay mouse model [AID592241, Type: Literature]
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18
[SID103207410]
Hypoglycemic activity in rat assessed as decrease in plasma glucose at 5 mg/kg, iv [AID592242, Type: Literature]
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19
[SID103207410]
Hypoglycemic activity in rat assessed as increase in insulin concentration at 5 mg/kg, iv [AID592243, Type: Literature]
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20
[SID103207410]
Binding affinity to amyloid beta (1 to 42) fibrils by change in fluorescence at 100 uM after 10 mins [AID475504, Type: Literature]
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