CHEMBL492595 (CID 44582410) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(8)
 
 
Unspecified(18)
 
 
BioAssay Types:
Literature(26)
 
 
 
BioActivity Types:
IC50(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 26    Data Row: 26   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103631849]
MIC 0.22Antimicrobial activity against methicillin-resistant Enterococcus faecalis ATCC 35556 by CLIS method [AID417513, Type: Literature]
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2
[SID103631849]
IC50 0.4Cytotoxicity against human HCT116 cells [AID417514, Type: Literature]
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3
[SID103631849]
MIC 0.9Antimicrobial activity against methicillin-resistant Staphylococcus aureus ATCC 29212 by CLIS method [AID417512, Type: Literature]
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4
[SID103631849]
MIC 1.79Antimicrobial activity against methicillin-resistant Staphylococcus aureus L32 clinical isolate by CLIS method [AID417510, Type: Literature]
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5
[SID103631849]
MIC 1.79Antimicrobial activity against methicillin-resistant Staphylococcus aureus L44 clinical isolate by CLIS method [AID417511, Type: Literature]
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6
[SID103631849]
 Inhibition of Staphylococcus aureus ATCC 29212 biofilm formation at MIC [AID417523, Type: Literature]
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7
[SID103631849]
 Inhibition of Enterococcus faecalis ATCC 35556 biofilm formation at MIC [AID417524, Type: Literature]
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8
[SID103631849]
 Inhibition of methicillin-susceptible Staphylococcus aureus ATCC 29212 biofilm formation assessed as visible growth after 24 hrs [AID417529, Type: Literature]
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9
[SID103631849]
 Inhibition of methicillin-susceptible Staphylococcus aureus ATCC 29212 biofilm formation assessed as concentration required to eradicate growth after 24 hrs [AID417530, Type: Literature]
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10
[SID103631849]
 Inhibition of Enterococcus faecalis ATCC 35556 biofilm formation assessed as visible growth after 24 hrs [AID417531, Type: Literature]
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11
[SID103631849]
 Inhibition of Enterococcus faecalis ATCC 35556 biofilm formation assessed as concentration required to eradicate growth after 24 hrs [AID417532, Type: Literature]
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12
[SID103631849]
 Cytotoxicity against human A549 cells [AID318598, Type: Literature]
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13
[SID103631849]
 Cytotoxicity against human HeLa cells [AID318597, Type: Literature]
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14
[SID103631849]
 Cytotoxicity against human HL60 cells [AID318596, Type: Literature]
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15
[SID103631849]
 Inhibition of methicillin-resistant Staphylococcus aureus L32 clinical isolate biofilm formation assessed as visible growth after 24 hrs [AID417525, Type: Literature]
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16
[SID103631849]
 Inhibition of methicillin-resistant Staphylococcus aureus L32 clinical isolate biofilm formation assessed as concentration required to eradicate growth after 24 hrs [AID417526, Type: Literature]
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17
[SID103631849]
 Inhibition of methicillin-resistant Staphylococcus aureus L44 clinical isolate biofilm formation assessed as visible growth after 24 hrs [AID417527, Type: Literature]
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18
[SID103631849]
 Inhibition of methicillin-resistant Staphylococcus aureus L44 clinical isolate biofilm formation assessed as concentration required to eradicate growth after 24 hrs [AID417528, Type: Literature]
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19
[SID103631849]
 Antimicrobial activity against methicillin-resistant Staphylococcus aureus L32 clinical isolate assessed as reduction in bacterial load at 2 X MIC over 24 hrs by time-kill assay [AID417515, Type: Literature]
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20
[SID103631849]
 Antimicrobial activity against methicillin-resistant Staphylococcus aureus L44 clinical isolate assessed as reduction in bacterial load at 2 X MIC over 24 hrs by time-kill assay [AID417516, Type: Literature]
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21
[SID103631849]
 Antimicrobial activity against methicillin-susceptible Staphylococcus aureus ATCC 29212 assessed as reduction in bacterial load at 2 X MIC over 24 hrs by time-kill assay [AID417517, Type: Literature]
View
22
[SID103631849]
 Antimicrobial activity against Enterococcus faecalis ATCC 35556 assessed as reduction in bacterial load at 2 X MIC over 24 hrs by time-kill assay [AID417518, Type: Literature]
View
23
[SID103631849]
 Antimicrobial activity against methicillin-resistant Staphylococcus aureus L32 clinical isolate assessed as reduction in bacterial load at 4 fold MIC over 24 hrs by time-kill assay [AID417519, Type: Literature]
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24
[SID103631849]
 Antimicrobial activity against methicillin-resistant Staphylococcus aureus L44 clinical isolate assessed as reduction in bacterial load at 4 fold MIC over 24 hrs by time-kill assay [AID417520, Type: Literature]
View
25
[SID103631849]
 Antimicrobial activity against methicillin-susceptible Staphylococcus aureus ATCC 29212 assessed as reduction in bacterial load at 4 fold MIC over 24 hrs by time-kill assay [AID417521, Type: Literature]
View
26
[SID103631849]
 Antimicrobial activity against Enterococcus faecalis ATCC 35556 assessed as reduction in bacterial load at 4 fold MIC over 24 hrs by time-kill assay [AID417522, Type: Literature]
View