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CHEMBL475761 (CID 44571449) - Compound BioActivity Data
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BioActivity Outcomes:
Active(6)
 
 
Inactive(8)
 
 
Inconclusive(1)
 
 
Unspecified(456)
 
 
Top Targets:
PTKc Abl(16)
 
 
PTKc EGFR(10)
 
 
PKc like(10)
 
 
STKc RSK N(8)
 
 
PTKc Kit(8)
 
 
BioAssay Types:
Literature(5)
 
 
 
Confirmatory(5)
 
 
 
 
BioActivity Types:
Potency(7)
 
 
 
 
AC50(2)
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 471    Data Row: 471   Total Pages: 24   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103610156]
IC50 0.005Inhibition of EGFR [AID367173, Type: Literature]
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2
[SID103610156]
IC50 0.25Inhibition of ErbB2 [AID367174, Type: Literature]
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3
[SID124350103]
Potency 0.8227qHTS for small molecule inhibitors of Yes1 kinase: Primary Screen [AID686947, Type: Literature]tyrosine-protein kinase Yes [Homo sapiens] [gi:4885661]
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4
[SID124350103]
Potency 9.9597qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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5
[SID124350103]
Potency 19.8722qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
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6
[SID124350103]
Potency 20.5749qHTS Assay for Inhibitors of Sea Pansy Luciferase from the GSK Published Protein Kinase Inhibitor Set [AID652015, Type: confirmatory]Renilla-luciferin 2-monooxygenase (EC 1.13.12.5) - sea pansy (Renilla reniformis) (fragment) [Renilla reniformis] [gi:84399]
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7
[SID103610156]
AC50 20.5749GSK_PKIS: Inhibition of Sea Pansy Luciferase (Data from PubChem: AID 652015) [NIH NCATS] [AID720834, Type: Literature]Renilla-luciferin 2-monooxygenase [gi:126502]
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8
[SID103610156]
GSK_PKIS: PDGFRB mean inhibition at 0.1 uM [Nanosyn] [AID651298, Type: other]Platelet-derived growth factor receptor beta [gi:129890]
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9
[SID103610156]
GSK_PKIS: PDGFRB mean inhibition at 1 uM [Nanosyn] [AID651299, Type: other]Platelet-derived growth factor receptor beta [gi:129890]
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10
[SID103610156]
GSK_PKIS: PDGFRA mean inhibition at 0.1 uM [Nanosyn] [AID651290, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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11
[SID103610156]
GSK_PKIS: PDGFRA mean inhibition at 1 uM [Nanosyn] [AID651291, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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12
[SID103610156]
GSK_PKIS: PDGFRA (D842V mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651292, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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13
[SID103610156]
GSK_PKIS: PDGFRA (D842V mutant) mean inhibition at 1 uM [Nanosyn] [AID651293, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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14
[SID103610156]
GSK_PKIS: PDGFRA (T674I mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651294, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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15
[SID103610156]
GSK_PKIS: PDGFRA (T674I mutant) mean inhibition at 1 uM [Nanosyn] [AID651295, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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16
[SID103610156]
GSK_PKIS: PDGFRA (V561D mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651296, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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17
[SID103610156]
GSK_PKIS: PDGFRA (V561D mutant) mean inhibition at 1 uM [Nanosyn] [AID651297, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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18
[SID103610156]
GSK_PKIS: CDK3/cyclinE mean inhibition at 0.1 uM [Nanosyn] [AID651168, Type: other]Cyclin-dependent kinase 3 [gi:231726]
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19
[SID103610156]
GSK_PKIS: CDK3/cyclinE mean inhibition at 1 uM [Nanosyn] [AID651169, Type: other]Cyclin-dependent kinase 3 [gi:231726]
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20
[SID103610156]
GSK_PKIS: MAPK3 mean inhibition at 0.1 uM [Nanosyn] [AID651198, Type: other]Mitogen-activated protein kinase 3 [gi:232066]
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