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CHEMBL490682 (CID 44564050) - Compound BioActivity Data
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BioActivity Outcomes:
Active(4)
 
 
BioAssay Types:
Literature(4)
 
 
BioActivity Types:
IC50(4)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 4    Data Row: 4   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103592105]
IC50 1.4Inhibition of Hsp90-dependent renatureation of firefily luciferase in rabbit reticulocyte lysate at 25 ug/mL [AID347501, Type: Literature]
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2
[SID103592105]
IC50 1.9Antiproliferative activity against ERalpha positive human MCF7 cells after 72 hrs by MTS/PMS assay [AID347503, Type: Literature]
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3
[SID103592105]
IC50 2.5Inhibition of Hsp90 in human SKBR3 cells assessed as down-regulation of Her2 protein by ELISA [AID347502, Type: Literature]
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4
[SID103592105]
IC50 4.8Antiproliferative activity against ERalpha negative/Her2 over expressing human SKBR3 cells after 72 hrs by MTS/PMS assay [AID347638, Type: Literature]
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