MONO TFA SALT (CID 44552613) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Probe(1)
 
 
Active(19)
 
 
Inactive(143)
 
 
Inconclusive(6)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(8)
 
 
7TM GPCR Srsx(4)
 
 
PKc(4)
 
 
 
 
Alpha TIF(4)
 
 
 
NR LBD Tlx PN..(3)
 
 
 
BioAssay Types:
Screening(135)
 
 
 
 
Confirmatory(28)
 
 
 
 
Literature(3)
 
 
Summary(1)
 
 
BioActivity Types:
Potency(24)
 
 
 
 
AC50(2)
 
 
 
EC50(2)
 
 
 
IC50(2)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 167    Data Row: 170   Total Pages: 4   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID87235992]
 Summary of probe development efforts to identify inhibitors of Wee1 degradation [AID1807, Type: summary]WEE1 homolog (S. pombe) [Homo sapiens] [gi:47123300]
View
2
[SID87235992]
 Summary of probe development efforts to identify inhibitors of Wee1 degradation [AID1807, Type: summary]WEE1 homolog (S. pombe) [Homo sapiens] [gi:47123300]
View
3
[SID87235992]
 Summary of probe development efforts to identify inhibitors of Wee1 degradation [AID1807, Type: summary]WEE1 homolog (S. pombe) [Homo sapiens] [gi:47123300]
View
4
[SID99495575]
AC50 1.79Identification of VIF Inhibitors Measured in Cell-Based System Using Imaging - 2108-01_Inhibitor_Dose_CherryPick_Activity [AID652241, Type: confirmatory]Vif [Human immunodeficiency virus 1] [gi:9629361]
View
5
[SID99495575]
Potency 2.2387qHTS for Inhibitors of TGF-b [AID588855, Type: confirmatory]Smad3 [Homo sapiens] [gi:18418623]
View
6
[SID99495575]
Potency 2.2387qHTS for Inhibitors of TGF-b [AID588855, Type: confirmatory]Smad3 [Homo sapiens] [gi:18418623]
View
7
[SID99495575]
IC50 2.971Luminescence-based cell-based high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) [AID624394, Type: confirmatory]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
View
8
[SID99495575]
IC50 2.971Luminescence-based cell-based high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) [AID624394, Type: confirmatory]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
View
9
[SID99495575]
IC50 2.971Luminescence-based cell-based high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) [AID624394, Type: confirmatory]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
View
10
[SID87235992]
EC50 6.188Late stage results from the probe development effort to identify inhibitors of Wee1 degradation. [AID2088_1, Type: screening]WEE1 homolog (S. pombe) [Homo sapiens] [gi:47123300]
View
11
[SID87235992]
EC50 6.188Late stage results from the probe development effort to identify inhibitors of Wee1 degradation. [AID2088_1, Type: screening]WEE1 homolog (S. pombe) [Homo sapiens] [gi:47123300]
View
12
[SID87235992]
EC50 6.188Late stage results from the probe development effort to identify inhibitors of Wee1 degradation. [AID2088_1, Type: screening]WEE1 homolog (S. pombe) [Homo sapiens] [gi:47123300]
View
13
[SID99495575]
IC50 8.229Counterscreen for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3):Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) [AID624395, Type: confirmatory]transactivating tegument protein VP16 [Human herpesvirus 1] [gi:9629429]
View
14
[SID99495575]
 HTS Assay for Peg3 Promoter Inhibitors [AID588405, Type: screening]Ppp1r15a gene product [Rattus norvegicus] [gi:78486550]
View
15
[SID87235992]
 Late stage results from the probe development effort to identify inhibitors of Wee1 degradation. [AID2088, Type: screening]WEE1 homolog (S. pombe) [Homo sapiens] [gi:47123300]
View
16
[SID87235992]
 Late stage results from the probe development effort to identify inhibitors of Wee1 degradation. [AID2088, Type: screening]WEE1 homolog (S. pombe) [Homo sapiens] [gi:47123300]
View
17
[SID87235992]
 Late stage results from the probe development effort to identify inhibitors of Wee1 degradation. [AID2088, Type: screening]WEE1 homolog (S. pombe) [Homo sapiens] [gi:47123300]
View
18
[SID99495575]
 Luminescence-based cell-based primary high throughput screening assay to identify activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM) [AID652017, Type: screening]SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, i [gi:119579215]
View
19
[SID99495575]
 Luminescence-based cell-based primary high throughput confirmation assay to identify activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM) [AID652260, Type: screening]SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, i [gi:119579215]
View
20
[SID99495575]
 Luminescence-based cell-based high throughput confirmation assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) [AID624378, Type: screening]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
View
21
[SID99495575]
 Luminescence-based cell-based high throughput confirmation assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) [AID624378, Type: screening]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
View
22
[SID99495575]
 Luminescence-based cell-based high throughput confirmation assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) [AID624378, Type: screening]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
View
23
[SID99495575]
 Identification of VIF Inhibitors Measured in Cell-Based System Using Imaging - 2108-01_Inhibitor_SinglePoint_HTS_Activity [AID602346, Type: screening]Vif [Human immunodeficiency virus 1] [gi:9629361]
View
24
[SID99495575]
 Counterscreen for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): Luminescence-based cell-based high throughput assay to identify nonselective inhibitors of the Steroidogenic acute regulatory protein (StAR) promoter or luminescence assay artifacts [AID651611, Type: screening]
View
25
[SID99495575]
 Luminescence-based cell-based high throughput confirmation assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651613, Type: screening]NR5A2 gene product [Homo sapiens] [gi:4504343]
View
26
[SID99495575]
 Luminescence-based cell-based high throughput confirmation assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651613, Type: screening]NR5A2 gene product [Homo sapiens] [gi:4504343]
View
27
[SID99495575]
 Luminescence-based cell-based primary high throughput screening assay to identify inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID602396, Type: screening]NR5A2 gene product [Homo sapiens] [gi:4504343]
View
28
[SID99495575]
 Luminescence-based cell-based primary high throughput screening assay to identify inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID602396, Type: screening]NR5A2 gene product [Homo sapiens] [gi:4504343]
View
29
[SID99495575]
 Counterscreen for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): Luminescence-based cell-based high throughput assay to identify inverse agonists of the Steroidogenic Factor 1 Nuclear Receptor (SF1; NR5A1) [AID651614, Type: screening]NR5A1 gene product [Homo sapiens] [gi:20070193]
View
30
[SID99495575]
 Counterscreen for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): Luminescence-based cell-based high throughput assay to identify inverse agonists of the Steroidogenic Factor 1 Nuclear Receptor (SF1; NR5A1) [AID651614, Type: screening]NR5A1 gene product [Homo sapiens] [gi:20070193]
View
31
[SID99495575]
 Counterscreen for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): Luminescence-based cell-based high throughput assay to identify inverse agonists of the Steroidogenic Factor 1 Nuclear Receptor (SF1; NR5A1) [AID651614, Type: screening]NR5A1 gene product [Homo sapiens] [gi:20070193]
View
32
[SID99495575]
 Counterscreen for activators of the GAA850 frataxin promoter: luminescence-based cell-based high throughput screening assay to identify activators of the GAA30 frataxin promoter [AID588350, Type: screening]
View
33
[SID99495575]
 Luminescence-based cell-based high throughput confirmation assay for activators of the GAA850 frataxin (FXN) promoter [AID588351, Type: screening]
View
34
[SID99495575]
 Luminescence-based cell-based primary high throughput screening assay to identify activators of the GAA850 frataxin (FXN) promoter [AID540364, Type: screening]
View
35
[SID99495575]
 uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay [AID588850, Type: screening]CFTR gene product [Homo sapiens] [gi:90421313]
View
36
[SID99495575]
 uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay [AID588850, Type: screening]CFTR gene product [Homo sapiens] [gi:90421313]
View
37
[SID87235992]
 Late stage results from the probe development effort to identify inhibitors of Wee1 degradation. [AID2088_3, Type: screening]WEE1 homolog (S. pombe) [Homo sapiens] [gi:47123300]
View
38
[SID87235992]
 Late stage results from the probe development effort to identify inhibitors of Wee1 degradation. [AID2088_3, Type: screening]WEE1 homolog (S. pombe) [Homo sapiens] [gi:47123300]
View
39
[SID87235992]
 Late stage results from the probe development effort to identify inhibitors of Wee1 degradation. [AID2088_3, Type: screening]WEE1 homolog (S. pombe) [Homo sapiens] [gi:47123300]
View
40
[SID99495575]
Potency 1.4125qHTS for Inhibitors of TGF-b: Cytotox Counterscreen [AID588856, Type: confirmatory]
View
41
[SID99495575]
AC50 52Identification of VIF Inhibitors- ruling Out Cytotoxic Compounds Measured in Cell-Based System Using Imaging - 2108-02_Inhibitor_Dose_CherryPick_Activity [AID652208, Type: confirmatory]Vif [Human immunodeficiency virus 1] [gi:9629361]
View
42
[SID87235992]
EC50 55.69Late stage results from the probe development effort to identify inhibitors of Wee1 degradation. [AID2088_2, Type: screening]cyclin B1 [Homo sapiens] [gi:119571691]
View
43
[SID87235992]
EC50 55.69Late stage results from the probe development effort to identify inhibitors of Wee1 degradation. [AID2088_2, Type: screening]cyclin B1 [Homo sapiens] [gi:119571691]
View
44
[SID87235992]
EC50 55.69Late stage results from the probe development effort to identify inhibitors of Wee1 degradation. [AID2088_2, Type: screening]cyclin B1 [Homo sapiens] [gi:119571691]
View
45
[SID99495575]
Potency qHTS for Inhibitors of WRN Helicase [AID651768, Type: confirmatory]WRN [Homo sapiens] [gi:3719421]
View
46
[SID99495575]
 HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_SinglePoint_HTS_Activity [AID652154, Type: screening]PAX8 [Homo sapiens] [gi:998701]
View
47
[SID99495575]
 Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) [AID588352, Type: screening]nuclear receptor coactivator 3 isoform a [Homo sapiens] [gi:32307126]
View
48
[SID99495575]
 Luminescence-based cell-based high throughput confirmation assay for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3) [AID588792, Type: screening]nuclear receptor coactivator 3 isoform a [Homo sapiens] [gi:32307126]
View
49
[SID99495575]
 Identification of inhibitors of RAD54 Measured in Biochemical System Using Plate Reader - 2159-01_Inhibitor_SinglePoint_HTS_Activity [AID602329, Type: screening]RAD54L gene product [Homo sapiens] [gi:216548193]
View
50
[SID99495575]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the Galanin Receptor 3 (GalR3) [AID651719, Type: screening]GALR3 gene product [Homo sapiens] [gi:4503907]
View