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CHEMBL1908395 (CID 44551653) - Compound BioActivity Data
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BioActivity Outcomes:
Active(238)
 
 
Unspecified(204)
 
 
Top Targets:
PKc(48)
 
 
 
PKc like(40)
 
 
 
STKc AGC(17)
 
 
 
PTKc Abl(16)
 
 
PTKc EGFR(12)
 
 
 
BioAssay Types:
Literature(442)
 
 
 
BioActivity Types:
Kd(442)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 442    Data Row: 442   Total Pages: 23   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID136941612]
Kd 0.00083Binding constant for RET(V804M) kinase domain [AID625124, Type: Literature]Proto-oncogene tyrosine-protein kinase receptor Ret [gi:547807]
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2
[SID136941612]
Kd 0.0012Binding constant for RET(V804L) kinase domain [AID625123, Type: Literature]Proto-oncogene tyrosine-protein kinase receptor Ret [gi:547807]
View
3
[SID136941612]
Kd 0.0015Binding constant for FLT3(D835Y) kinase domain [AID624936, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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4
[SID136941612]
Kd 0.0023Binding constant for KIT(L576P) kinase domain [AID624790, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
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5
[SID136941612]
Kd 0.0024Binding constant for FLT3(D835H) kinase domain [AID624935, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
6
[SID136941612]
Kd 0.0032Binding constant for CSF1R kinase domain [AID624995, Type: Literature]Macrophage colony-stimulating factor 1 receptor [gi:547770]
View
7
[SID136941612]
Kd 0.0036Binding constant for KIT kinase domain [AID624786, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
8
[SID136941612]
Kd 0.0041Binding constant for AMPK-alpha2 kinase domain [AID625047, Type: Literature]5'-AMP-activated protein kinase catalytic subunit alpha-2 [gi:20178276]
View
9
[SID136941612]
Kd 0.0042Binding constant for FLT3(ITD) kinase domain [AID624937, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
10
[SID136941612]
Kd 0.0053Binding constant for AXL kinase domain [AID624840, Type: Literature]Tyrosine-protein kinase receptor UFO [gi:239938818]
View
11
[SID136941612]
Kd 0.0058Binding constant for TYK2(JH1domain-catalytic) kinase domain [AID624912, Type: Literature]Non-receptor tyrosine-protein kinase TYK2 [gi:56405328]
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12
[SID136941612]
Kd 0.006Binding constant for KIT(V559D,V654A) kinase domain [AID624793, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
13
[SID136941612]
Kd 0.0064Binding constant for RET(M918T) kinase domain [AID625122, Type: Literature]Proto-oncogene tyrosine-protein kinase receptor Ret [gi:547807]
View
14
[SID136941612]
Kd 0.0072Binding constant for TAK1 kinase domain [AID624724, Type: Literature]Mitogen-activated protein kinase kinase kinase 7 [gi:12643557]
View
15
[SID136941612]
Kd 0.0077Binding constant for KIT(V559D) kinase domain [AID624791, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
16
[SID136941612]
Kd 0.0092Binding constant for RET kinase domain [AID625121, Type: Literature]Proto-oncogene tyrosine-protein kinase receptor Ret [gi:547807]
View
17
[SID136941612]
Kd 0.0094Binding constant for DDR1 kinase domain [AID624850, Type: Literature]Epithelial discoidin domain-containing receptor 1 [gi:729008]
View
18
[SID136941612]
Kd 0.0099Binding constant for JAK2(JH1domain-catalytic) kinase domain [AID624973, Type: Literature]Tyrosine-protein kinase JAK2 [gi:12643404]
View
19
[SID136941612]
Kd 0.0099Binding constant for CHEK1 kinase domain [AID624831, Type: Literature]Serine/threonine-protein kinase Chk1 [gi:317373343]
View
20
[SID136941612]
Kd 0.01Binding constant for ACVR1B kinase domain [AID624943, Type: Literature]Activin receptor type-1B [gi:547775]
View