Bookmark and Share
resveratrol (CID 445154) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(539)
 
 
Inactive(1443)
 
 
Inconclusive(240)
 
 
Unspecified(861)
 
 
Top Targets:
7TM GPCR Srx(47)
 
 
 
NR LBD ER(43)
 
 
 
 
 
NR LBD PPAR(40)
 
 
 
 
7TM GPCR Srsx(39)
 
 
 
p450(28)
 
 
 
 
 
BioAssay Types:
Literature(1170)
 
 
 
 
 
Confirmatory(1073)
 
 
 
 
 
Screening(663)
 
 
 
 
 
Summary(73)
 
 
 
 
BioActivity Types:
Potency(815)
 
 
 
 
 
IC50(358)
 
 
 
 
 
EC50(35)
 
 
 
 
Ki(22)
 
 
 
AC50(10)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 2497    Data Row: 3083   Total Pages: 155   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103259583]
IC50 2.25e-05Antiproliferative activity against human HeLa cells assessed as cell viability after 48 hrs by SRB assay [AID620775, Type: Literature]
View
2
[SID103259583]
IC50 4.03e-05Antiproliferative activity against human SK-N-SH cells assessed as cell viability after 48 hrs by SRB assay [AID620727, Type: Literature]
View
3
[SID103259583]
IC50 4.47e-05Antiproliferative activity against human A549 cells assessed as cell viability after 48 hrs by SRB assay [AID620728, Type: Literature]
View
4
[SID103259583]
IC50 7.91e-05Antiproliferative activity against human MCF7 cells assessed as cell viability after 48 hrs by SRB assay [AID620726, Type: Literature]
View
5
[SID144208572]
Potency-Replicate_1 0.0088qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
6
[SID103259583]
Kd 0.054Binding affinity to human quinone reductase 2 by ITC analysis [AID770330, Type: Literature]Ribosyldihydronicotinamide dehydrogenase [quinone] [gi:317373581]
View
7
[SID103259583]
IC50 0.05888Inhibition of recombinant firefly luciferase after 20 mins by luminescence assay [AID725947, Type: Literature]Luciferin 4-monooxygenase [gi:126501]
View
8
[SID103259583]
Ki 0.088Competitive inhibition of human quinone reductase 2 using menadione/N-methyldihydronicotinamide as substrate after 10 mins by double-reciprocal plot analysis [AID770334, Type: Literature]Ribosyldihydronicotinamide dehydrogenase [quinone] [gi:317373581]
View
9
[SID103259583]
Ki 0.169Binding affinity for aryl hydrocarbon receptor (AhR) of rabbit liver cytosol incubated with 0.2 nM [3H]-TCDD; Antagonist [AID239550, Type: Literature]
View
10
[SID103259583]
IC50 0.173Inhibition of TNF-alpha-induced NF-kappaB activity expressed in HEK293 cells after 48 hrs by luciferase reporter gene assay [AID491619, Type: Literature]
View
11
[SID103259583]
IC50 0.38Inhibition of ovine COX1 [AID271286, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
View
12
[SID103259583]
IC50 0.449DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine) [AID625150, Type: confirmatory]Amine oxidase [flavin-containing] A [gi:113978]
View
13
[SID103259583]
IC50 0.45Inhibition of human recombinant NQO2 by spectrophotometry [AID459814, Type: Literature]Ribosyldihydronicotinamide dehydrogenase [quinone] [gi:317373581]
View
14
[SID103259583]
IC50 0.45Inhibition of human recombinant NQO2 assessed as reduction of DCPIP by spectrophotometry [AID479979, Type: Literature]Ribosyldihydronicotinamide dehydrogenase [quinone] [gi:317373581]
View
15
[SID103259583]
Kd 0.5Binding affinity to amyloid beta (1 to 40) in APP/PS1 transgenic mouse brain by fluorescence titration analysis [AID528473, Type: Literature]
View
16
[SID103259583]
IC50 0.535Inhibition of ovine COX1 by measuring PGE2 [AID289278, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
View
17
[SID103259583]
EC50 0.58Inhibition of RML prion protein infected in mouse dividing ScN2a-cl3 cells expressing full length mouse PrP assessed as reduction of PrPsc level after 5 days by Western blotting analysis [AID1057861, Type: Literature]
View
18
[SID103259583]
IC50 0.6DRUGMATRIX: CYP450, 3A4 enzyme inhibition (substrate: 7-Benzyloxy-4-(trifluoromethyl)-coumarin) [AID625251, Type: confirmatory]Cytochrome P450 3A4 [gi:116241312]
View
19
[SID103259583]
IC50 0.625DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid) [AID625243, Type: confirmatory]Prostaglandin G/H synthase 1 [gi:317373262]
View
20
[SID144208572]
Potency-Replicate_1 0.6922qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
View