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BioActivity Data for Compound MLS003128757 (CID 44502277)

BioActivity Outcomes:
Active(4)
 
 
Inactive(253)
 
 
Inconclusive(2)
 
 
Top Targets:
7tm 4(17)
 
 
RasGEF(4)
 
 
CAP ED(4)
 
 
Pyruvate Kina..(3)
 
 
ABCC CFTR1(3)
 
 
BioAssay Types:
Screening(195)
 
 
Confirmatory(52)
 
 
 
 
Literature(9)
 
 
BioAssay Categories:
Organism-base..(7)
 
 
Biochemical(57)
 
 
Toxicity(4)
 
 
Cell-based(85)
 
 
 
BioActivity Types:
Potency(45)
 
 
 
 
IC50(5)
 
 
AC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 225    Data Row: 259   Total Pages: 13   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID99358988]
Potency 7.0795qHTS of Trypanosoma Brucei Inhibitors: Confirmatory Assay for Cherry-picked Compounds [AID720569, Type: confirmatory]hypothetical protein, conserved [Trypanosoma brucei] [gi:62359610]
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2
[SID99358988]
Potency 7.9433qHTS of Trypanosoma Brucei Inhibitors: Orthogonal Assay for Cherry-picked Compounds [AID720584, Type: confirmatory]hypothetical protein, conserved [Trypanosoma brucei] [gi:62359610]
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3
[SID99358988]
Potency 7.9433qHTS of Trypanosoma Brucei Inhibitors [AID624173, Type: confirmatory]hypothetical protein, conserved [Trypanosoma brucei] [gi:62359610]
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4
[SID99358988]
Potency 20.5962qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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5
[SID99358988]
Potency qHTS of GLP-1 Receptor Inverse Agonists: Cytotox Screen [AID624418, Type: confirmatory]
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6
[SID99358988]
Counterscreen of compound fluorescence effects on High-throughput multiplex microsphere screening for inhibitors of toxin protease [AID624483, Type: screening]
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7
[SID99358988]
Luminescence Cell-Based Primary HTS to identify inhibitors of the oncoprotein EWS/Fli transcriptional activity Measured in Cell-Based System Using Plate Reader - 7014-01_Inhibitor_SinglePoint_HTS_Activity [AID651661, Type: screening]
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8
[SID99358988]
MLPCN PGC1a Modulators Measured in Cell-Based System Using Plate Reader - 2139-01_Inhibitor_SinglePoint_HTS_Activity [AID651687, Type: screening]
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9
[SID99358988]
Flow Cytometric HTS Screening for Inhibitors of Lytic Granule Exocytosis with MLPCN Compound Library [AID651702, Type: screening]
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10
[SID99358988]
HTS for the detection of C. neoformans cell lysis via adenylate kinase (AK) release Measured in Microorganism System Using Plate Reader - 2162-01_Inhibitor_SinglePoint_HTS_Activity [AID651654, Type: screening]
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11
[SID99358988]
DENV2 CPE-Based HTS Measured in Cell-Based and Microorganism Combination System Using Plate Reader - 2149-01_Other_SinglePoint_HTS_Activity [AID651640, Type: screening]
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12
[SID99358988]
HIV entry: Env-mediated Cell Fusion Measured in Cell-Based System Using Plate Reader - 7013-01_Inhibitor_SinglePoint_HTS_Activity [AID651610, Type: screening]
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13
[SID99358988]
uHTS identification of small molecule Triacylglycerol inhbitors in a fluoresence assay [AID651582, Type: screening]
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14
[SID99358988]
Fluorescence-based biochemical primary high throughput screening assay to identify molecules that bind r(CAG) RNA repeats [AID651821, Type: screening]
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15
[SID99358988]
Potency qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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16
[SID99358988]
MLPCN PGC1a Modulators Measured in Cell-Based System Using Plate Reader - 2139-01_Activator_SinglePoint_HTS_Activity [AID651723, Type: screening]
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17
[SID85809352]
AC50_uM NIH/3T3 (mouse embryonic fibroblast) toxicity Measured in Cell-Based System Using Plate Reader - 2138-02_Inhibitor_Dose_DryPowder_Activity_Set2 [AID652280, Type: confirmatory]
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18
[SID99358988]
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl) [AID588664, Type: screening]tyrosine-protein kinase ABL1 isoform a [Homo sapiens] [gi:62362414]
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19
[SID99358988]
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl) [AID588664, Type: screening]ras and Rab interactor 1 [Homo sapiens] [gi:68989256]
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20
[SID99358988]
Potency qHTS for Inhibitors of Glutaminase (GLS) [AID624170, Type: confirmatory]GLS protein [Homo sapiens] [gi:71051501]
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