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BRD-K18074178-001-01-4 (CID 44499857) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(7)
 
 
Inactive(48)
 
 
Top Targets:
CD36(4)
 
 
 
CASc(1)
 
 
zf-HC5HC2H 2(1)
 
 
HLH(1)
 
 
OAT like(1)
 
 
BioAssay Types:
Screening(48)
 
 
 
Confirmatory(7)
 
 
 
BioActivity Types:
AC50(7)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 53    Data Row: 55   Total Pages: 3   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID85806885]
AC50_uM 1.501HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_Dose_DryPowder_Activity [AID540354, Type: confirmatory]
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2
[SID85806885]
AC50_uM 1.79HDL Orthogonal Assay: Alexa 488-HDL Measured in Cell-Based System Using Plate Reader - 2085-03_Inhibitor_Dose_DryPowder_Activity [AID588777, Type: confirmatory]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
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3
[SID85806885]
AC50_uM 16.08HDL Counter Assay: 3/24 Cytotox Measured in Cell-Based System Using Plate Reader - 2085-02_Inhibitor_Dose_DryPowder_Activity_Set3 [AID588826, Type: confirmatory]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
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4
[SID85806885]
AC50_uM 29.8HDL Counter Assay: 3/24 Cytotox Measured in Cell-Based System Using Plate Reader - 2085-02_Inhibitor_Dose_DryPowder_Activity_Set4 [AID588842, Type: confirmatory]
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5
[SID85806885]
AC50_uM 66.451HDL Counter Assay: 3/24 Cytotox Measured in Cell-Based System Using Plate Reader - 2085-02_Inhibitor_Dose_DryPowder_Activity [AID540246, Type: confirmatory]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
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6
[SID85806885]
HIV entry: Env-mediated Cell Fusion Measured in Cell-Based System Using Plate Reader - 7013-01_Inhibitor_SinglePoint_HTS_Activity [AID651610, Type: screening]
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7
[SID85806885]
Fluorescence Cell-Based Primary HTS to Identify Reactive Oxygen Species Inducers in Cancer Cells Measured in Cell-Based System Using Plate Reader and Imaging Combination - 2044-01_Activator_SinglePoint_HTS_Activity [AID624156, Type: screening]
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8
[SID85806885]
Inhibition of T.cruzi proliferation in culture Measured in Cell-Based System Using Plate Reader - 2138-01_Inhibitor_SinglePoint_HTS_Activity [AID624255, Type: screening]
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9
[SID85806885]
AC50_uM HDL Counter Assay: 3/24 Cytotox Measured in Cell-Based System Using Plate Reader - 2085-11_Inhibitor_Dose_DryPowder_Activity [AID588830, Type: confirmatory]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
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10
[SID85806885]
AC50_uM HDL Counter Assay: 3/24 Cytotox Measured in Cell-Based System Using Plate Reader - 2085-02_Inhibitor_Dose_DryPowder_Activity_Set5 [AID602126, Type: confirmatory]
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11
[SID85806885]
HTS for suppressors of simvastatin-induced mytoxicity in differentiated C2C12 cells Measured in Cell-Based System Using Plate Reader - 2112-01_Suppressor_SinglePoint_HTS_Activity [AID602340, Type: screening]
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12
[SID85806885]
Small molecule inhibitors of miR122 Measured in Cell-Based System Using Plate Reader - 2144-01_Inhibitor_SinglePoint_HTS_Activity [AID602342, Type: screening]
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13
[SID85806885]
Whole cell Yeast HTS to identify compounds modulating the fidelity of the start codon recognition in eukaryotes. Measured in Whole Organism System Using Plate Reader - 2155-01_Other_SinglePoint_HTS_Activity [AID602363, Type: screening]
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14
[SID85806885]
Small molecule inhibitors of miR122 Measured in Cell-Based System Using Plate Reader - 2144-01_Activator_SinglePoint_HTS_Activity [AID623901, Type: screening]
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15
[SID85806885]
Fluorescence Cell-Based Primary HTS to Measure Inhibition of Y box Binding Protein 1 Expression [AID434959, Type: screening]
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16
[SID85806885]
Detect Cellular ATP-levels in INS-1E Cells Measured in Cell-Based System Using Plate Reader - 2061-01_Inhibitor_SinglePoint_HTS_Activity [AID488910, Type: screening]
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17
[SID85806885]
Luminescence Cell-Based Primary HTS to Measure Viability of BJeLR cells [AID2275, Type: screening]
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18
[SID85806885]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of the Sonic Hedgehog Signaling Pathway [AID2313, Type: screening]
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19
[SID85806885]
Luminescence Cell-Based Primary HTS to Identify Activators of the Reversal of PD-1 Mediated Inhibitors of T-Cell Inhibition [AID2316, Type: screening]
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20
[SID85806885]
DENV2 CPE-Based HTS Measured in Cell-Based and Microorganism Combination System Using Plate Reader - 2149-01_Other_SinglePoint_HTS_Activity [AID651640, Type: screening]
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