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SureCN12697319 (CID 44494873) - Compound BioActivity Data
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BioActivity Outcomes:
Active(8)
 
 
Inactive(59)
 
 
Inconclusive(2)
 
 
Top Targets:
HLH(2)
 
 
CASc(1)
 
 
OAT like(1)
 
 
DUF3371(1)
 
 
RHD-n NFkB1(1)
 
 
BioAssay Types:
Screening(47)
 
 
 
Confirmatory(17)
 
 
 
 
BioActivity Types:
IC50(11)
 
 
 
AC50(6)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 65    Data Row: 69   Total Pages: 4   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID134216489]
Average IC50 (uM) 0.00042Inhibition of intracellular CAI/72 strain of Trypanosoma cruzi in bovine embryo skeletal muscle cells: high content imaging Measured in Cell-Based System Using Imaging - 2138-07_Inhibitor_SinglePoint_DryPowder_Activity [AID651885, Type: confirmatory]
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2
[SID134216489]
AC50_uM 0.0116Inhibition of T.cruzi proliferation in culture Measured in Cell-Based System Using Plate Reader - 2138-01_Inhibitor_Dose_DryPowder_Activity_Set2 [AID652275, Type: confirmatory]
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3
[SID134216489]
AC50_uM 0.0252Inhibition of T.cruzi proliferation in culture Measured in Cell-Based System Using Plate Reader - 2138-01_Inhibitor_Dose_DryPowder_Activity [AID651845, Type: confirmatory]
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4
[SID134216489]
IC50_uM 0.059Inhibition of T. cruzi Tulahuen strain amastigotes in L-6 muscle cells Measured in Cell-Based and Microorganism Combination System Using Plate Reader - 2138-03_Inhibitor_Dose_DryPowder_Activity [AID651890, Type: confirmatory]
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5
[SID85801692]
AC50_uM 0.08Intracellular Trypanosomes Measured in Cell-Based/Microorganism System Using Plate Reader - 2017-01_Inhibitor_Dose_CherryPick_Activity_Set3 [AID651818, Type: confirmatory]
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6
[SID134216489]
Cidal vs. static assay: inhibition of T. cruzi (CAI/72) after prolonged treatment and treatment withdrawal Measured in Cell-Based System Using Imaging - 2138-08_Inhibitor_SinglePoint_DryPowder_Activity_Set2 [AID651869, Type: other]
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7
[SID134216489]
Cidal vs. static assay: inhibition of T. cruzi (CAI/72) after prolonged treatment and treatment withdrawal Measured in Cell-Based System Using Imaging - 2138-08_Inhibitor_SinglePoint_DryPowder_Activity [AID651877, Type: other]
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8
[SID85801692]
Intracellular Trypanosomes Measured in Cell-Based/Microorganism System Using Plate Reader - 2017-01_Inhibitor_SinglePoint_HTS_Activity_Set2 [AID651903, Type: screening]
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9
[SID85801692]
IC50_uM 2.78Inhibition of T. cruzi Tulahuen strain amastigotes in L-6 muscle cells Measured in Cell-Based and Microorganism Combination System Using Plate Reader - 2138-03_Inhibitor_Dose_CherryPick_Activity [AID651881, Type: confirmatory]
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10
[SID85801692]
IC50_uM 2.78Inhibition of Plasmodium falcipirum NF54 Measured in Cell-Based System Using Plate Reader - 2138-11_Inhibitor_Dose_CherryPick_Activity [AID651888, Type: confirmatory]
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11
[SID134216489]
IC50_uM 2.935Inhibition of Plasmodium falcipirum NF54 Measured in Cell-Based System Using Plate Reader - 2138-11_Inhibitor_Dose_DryPowder_Activity [AID651889, Type: confirmatory]
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12
[SID134216489]
IC50_uM 3.625Inhibition of Trypanosoma brucei rhodesiense STIB900 Measured in Cell-Based System Using Plate Reader - 2138-05_Inhibitor_Dose_DryPowder_Activity [AID651894, Type: confirmatory]
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13
[SID85801692]
IC50_uM 6.15Inhibition of Trypanosoma brucei rhodesiense STIB900 Measured in Cell-Based System Using Plate Reader - 2138-05_Inhibitor_Dose_CherryPick_Activity [AID651893, Type: confirmatory]
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14
[SID85801692]
IC50_uM 43.7L-6 rat myocyte cell toxicity Measured in Cell-Based System Using Plate Reader - 2138-06_Inhibitor_Dose_CherryPick_Activity [AID651896, Type: confirmatory]
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15
[SID134216489]
IC50_uM 47.5L-6 rat myocyte cell toxicity Measured in Cell-Based System Using Plate Reader - 2138-06_Inhibitor_Dose_DryPowder_Activity [AID651895, Type: confirmatory]
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16
[SID85801692]
IC50_uM 100Inhibition of L. donovani axenic amastigotes Measured in Cell-Based System Using Plate Reader - 2138-04_Inhibitor_Dose_CherryPick_Activity [AID651891, Type: confirmatory]
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17
[SID134216489]
IC50_uM 100Inhibition of L. donovani axenic amastigotes Measured in Cell-Based System Using Plate Reader - 2138-04_Inhibitor_Dose_DryPowder_Activity [AID651892, Type: confirmatory]
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18
[SID85801692]
Luminescence Cell-Based Primary HTS to Measure Viability of BJeLR cells [AID2275, Type: screening]
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19
[SID85801692]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of the Sonic Hedgehog Signaling Pathway [AID2313, Type: screening]
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20
[SID85801692]
Fluorescence Cell-Based Primary HTS to Measure Inhibition of Y box Binding Protein 1 Expression [AID434959, Type: screening]
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