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SureCN12474983 (CID 44493436) - Compound BioActivity Data
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BioActivity Outcomes:
Probe(1)
 
 
Active(12)
 
 
Inactive(57)
 
 
Inconclusive(4)
 
 
Top Targets:
HLH(2)
 
 
CASc(1)
 
 
OAT like(1)
 
 
DUF3371(1)
 
 
RHD-n NFkB1(1)
 
 
BioAssay Types:
Screening(48)
 
 
 
 
Confirmatory(20)
 
 
 
 
Summary(1)
 
 
BioActivity Types:
IC50(12)
 
 
 
AC50(8)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 68    Data Row: 74   Total Pages: 4   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID152146810]
Broad Institute Inhibition of T.cruzi replication in culture Inhibitor Probe Project [AID624280, Type: summary]
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2
[SID134216491]
AC50_uM 0.000457Inhibition of T.cruzi proliferation in culture Measured in Cell-Based System Using Plate Reader - 2138-01_Inhibitor_Dose_DryPowder_Activity [AID651845, Type: confirmatory]
View
3
[SID134216491]
Average IC50 (uM) 0.00066Inhibition of intracellular CAI/72 strain of Trypanosoma cruzi in bovine embryo skeletal muscle cells: high content imaging Measured in Cell-Based System Using Imaging - 2138-07_Inhibitor_SinglePoint_DryPowder_Activity [AID651885, Type: confirmatory]
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4
[SID135701934]
AC50_uM 0.00442Inhibition of T.cruzi proliferation in culture Measured in Cell-Based System Using Plate Reader - 2138-01_Inhibitor_Dose_DryPowder_Activity_Set2 [AID652275, Type: confirmatory]
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5
[SID134216491]
IC50_uM 0.0295Inhibition of T. cruzi Tulahuen strain amastigotes in L-6 muscle cells Measured in Cell-Based and Microorganism Combination System Using Plate Reader - 2138-03_Inhibitor_Dose_DryPowder_Activity [AID651890, Type: confirmatory]
View
6
[SID85800201]
AC50_uM 0.08Intracellular Trypanosomes Measured in Cell-Based/Microorganism System Using Plate Reader - 2017-01_Inhibitor_Dose_CherryPick_Activity_Set3 [AID651818, Type: confirmatory]
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7
[SID85800201]
IC50_uM 1.02Inhibition of Plasmodium falcipirum NF54 Measured in Cell-Based System Using Plate Reader - 2138-11_Inhibitor_Dose_CherryPick_Activity [AID651888, Type: confirmatory]
View
8
[SID85800201]
IC50_uM 1.02Inhibition of T. cruzi Tulahuen strain amastigotes in L-6 muscle cells Measured in Cell-Based and Microorganism Combination System Using Plate Reader - 2138-03_Inhibitor_Dose_CherryPick_Activity [AID651881, Type: confirmatory]
View
9
[SID135701934]
IC50(uM) 13.2Inhibition of Trypanosoma cruzi Cruzain Measured in Biochemical System Using Plate Reader - 2138-09_Inhibitor_SinglePoint_DryPowder_Activity [AID651897, Type: confirmatory]cruzain [Trypanosoma cruzi] [gi:162048]
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10
[SID85800201]
IC50_uM 14.4L-6 rat myocyte cell toxicity Measured in Cell-Based System Using Plate Reader - 2138-06_Inhibitor_Dose_CherryPick_Activity [AID651896, Type: confirmatory]
View
11
[SID85800201]
Intracellular Trypanosomes Measured in Cell-Based/Microorganism System Using Plate Reader - 2017-01_Inhibitor_SinglePoint_HTS_Activity_Set2 [AID651903, Type: screening]
View
12
[SID135701934]
Cidal vs. static assay: inhibition of T. cruzi (CAI/72) after prolonged treatment and treatment withdrawal Measured in Cell-Based System Using Imaging - 2138-08_Inhibitor_SinglePoint_DryPowder_Activity_Set2 [AID651869, Type: other]
View
13
[SID135701934]
Cidal vs. static assay: inhibition of T. cruzi (CAI/72) after prolonged treatment and treatment withdrawal Measured in Cell-Based System Using Imaging - 2138-08_Inhibitor_SinglePoint_DryPowder_Activity [AID651877, Type: other]
View
14
[SID134216491]
IC50_uM 0.504Inhibition of Plasmodium falcipirum NF54 Measured in Cell-Based System Using Plate Reader - 2138-11_Inhibitor_Dose_DryPowder_Activity [AID651889, Type: confirmatory]
View
15
[SID134216491]
IC50_uM 1.495Inhibition of Trypanosoma brucei rhodesiense STIB900 Measured in Cell-Based System Using Plate Reader - 2138-05_Inhibitor_Dose_DryPowder_Activity [AID651894, Type: confirmatory]
View
16
[SID85800201]
IC50_uM 5.78Inhibition of Trypanosoma brucei rhodesiense STIB900 Measured in Cell-Based System Using Plate Reader - 2138-05_Inhibitor_Dose_CherryPick_Activity [AID651893, Type: confirmatory]
View
17
[SID134216491]
IC50_uM 8.4Inhibition of L. donovani axenic amastigotes Measured in Cell-Based System Using Plate Reader - 2138-04_Inhibitor_Dose_DryPowder_Activity [AID651892, Type: confirmatory]
View
18
[SID85800201]
IC50_uM 13.2Inhibition of L. donovani axenic amastigotes Measured in Cell-Based System Using Plate Reader - 2138-04_Inhibitor_Dose_CherryPick_Activity [AID651891, Type: confirmatory]
View
19
[SID134216491]
IC50_uM 17.1L-6 rat myocyte cell toxicity Measured in Cell-Based System Using Plate Reader - 2138-06_Inhibitor_Dose_DryPowder_Activity [AID651895, Type: confirmatory]
View
20
[SID152146810]
AC50_uM NIH/3T3 (mouse embryonic fibroblast) toxicity Measured in Cell-Based System Using Plate Reader - 2138-02_Inhibitor_Dose_DryPowder_Activity_Set2 [AID652280, Type: confirmatory]
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