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trichostatin A (CID 444732) - Compound BioActivity Data
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BioActivity Outcomes:
Active(563)
 
 
Inactive(130)
 
 
Inconclusive(14)
 
 
Unspecified(86)
 
 
Top Targets:
HDAC1(56)
 
 
 
HDAC4(34)
 
 
 
HDAC8(33)
 
 
 
 
HDAC6-dom1(33)
 
 
 
HDAC3(26)
 
 
 
BioAssay Types:
Literature(689)
 
 
 
 
 
Confirmatory(90)
 
 
 
 
 
Screening(6)
 
 
BioActivity Types:
IC50(448)
 
 
 
 
Potency(81)
 
 
 
 
Ki(16)
 
 
AC50(12)
 
 
EC50(12)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 598    Data Row: 793   Total Pages: 40   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103174338]
IC50 0.00015Inhibition of HDAC1 [AID488273, Type: Literature]
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2
[SID103174338]
Ki 0.0002Inhibition of human HDAC1 [AID496801, Type: Literature]Histone deacetylase 1 [gi:2498443]
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3
[SID103174338]
IC50 0.0004Inhibitory activity against maize Histone deacetylase 1-B [AID90672, Type: Literature]
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4
[SID103174338]
IC50 0.0004Inhibitory concentration against maize histone deacetylase 1-B (class I HDAC) [AID241538, Type: Literature]
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5
[SID103174338]
IC50 0.0004Inhibition of maize HD1B [AID273168, Type: Literature]Histone deacetylase [gi:75267996]
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6
[SID103174338]
IC50 0.0004Inhibition of maize histone deacetylase 1B [AID384316, Type: Literature]Histone deacetylase [gi:75267996]
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7
[SID103174338]
IC50 0.0004Inhibition of human HDAC6 [AID417649, Type: Literature]Histone deacetylase 6 [gi:205371758]
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8
[SID103174338]
IC50 0.00042Inhibition of human HDAC6 by fluorimetric assay [AID541652, Type: Literature]Histone deacetylase 6 [gi:205371758]
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9
[SID103174338]
Ki 0.0005Inhibition of human HDAC3 [AID496803, Type: Literature]Histone deacetylase 3 [gi:3334210]
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10
[SID103174338]
IC50 0.0006Inhibition of HDAC3 [AID488275, Type: Literature]
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11
[SID103174338]
IC50 0.0006Inhibition of Plasmodium falciparum HDAC1 expressed in Drosophila melanogaster S2 cells [AID414980, Type: Literature]Histone deacetylase [gi:74849912]
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12
[SID103174338]
Ki 0.00065Inhibition of human HDAC2 [AID496802, Type: Literature]Histone deacetylase 2 [gi:68068066]
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13
[SID96099520]
AC50_uM 0.00075Fluorescence Biochemical Dose Confirmation to Identify Inhibitors of Yeast HDACs [AID463208, Type: confirmatory]unnamed protein product [Saccharomyces cerevisiae] [gi:1360328]
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14
[SID103174338]
IC50 0.0008Inhibitory concentration against maize histone deacetylase 1-A (class IIa HDAC) [AID241537, Type: Literature]
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15
[SID103174338]
IC50 0.0008Inhibition of maize HD1A [AID273167, Type: Literature]
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16
[SID103174338]
IC50 0.0008Inhibition of maize histone deacetylase 1A [AID384317, Type: Literature]
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17
[SID103174338]
IC50 0.0008Inhibitory activity afgainst maize Histone deacetylase 1-A [AID90671, Type: Literature]
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18
[SID103174338]
IC50 0.0008Inhibition of HDAC6 by in vitro deacetylation assay [AID524999, Type: Literature]
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19
[SID103174338]
Ki 0.00087Inhibition of human recombinant HDAC1 by Michaelis-Menten equation analysis [AID760390, Type: Literature]Histone deacetylase 1 [gi:2498443]
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20
[SID103174338]
IC50 0.0009Inhibition of human recombinant HDAC6 expressed in baculovirus/sf9 cells using RHKKAc as substrate [AID769931, Type: Literature]Histone deacetylase 6 [gi:205371758]
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