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Ergosterol (CID 444679) - Compound BioActivity Data
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BioActivity Outcomes:
Active(4)
 
 
Inactive(16)
 
 
Inconclusive(1)
 
 
Unspecified(8)
 
 
Top Targets:
NOS oxygenase..(1)
 
 
GT1 Gtf like(1)
 
 
BioAssay Types:
Literature(19)
 
 
 
 
 
BioActivity Types:
IC50(8)
 
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 29    Data Row: 29   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID104248738]
IC50 27.9Antiinflammatory activity in human PMNC cells assessed as inhibition of fMLP-induced NOX-dependent ROS production up to 50 uM [AID550017, Type: Literature]
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2
[SID104248738]
IC50 27.9Inhibition of NOX in fMLP-induced PMN cells assessed as NO production [AID552869, Type: Literature]
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3
[SID104248738]
IC50 30.6Inhibition of iNOS in mouse BV2 microglial cells assessed as NO production [AID552870, Type: Literature]Nitric oxide synthase, inducible [gi:266649]
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4
[SID104248738]
IC50 30.6Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced iNOS-dependent nitrite production after 24 hrs by Griess method [AID550015, Type: Literature]
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5
[SID104248738]
Antibacterial activity against Legionella pneumophila Corby by microtiter plate assay [AID592502, Type: Literature]
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6
[SID104248738]
Cytotoxicity against Homo sapiens (human) HeLa cells after 48 hr by MTT assay [AID1095934, Type: other]
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7
[SID104248738]
Inhibition of TNFalpha-induced NF-kappaB activity (unknown origin) expressed in HeLa cells cotreated with compound and 10 ng/ml TNF-alpha for 24 hr by reporter gene assay [AID1095935, Type: other]
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8
[SID104248738]
Specific activity of expressed human recombinant UGT1A1 [AID624606, Type: Literature]UDP-glucuronosyltransferase 1-1 [gi:136729]
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9
[SID104248738]
Antibacterial activity against Staphylococcus aureus MTCC 96 assessed as growth inhibition at 2 mg/mL after 24 hr by disk diffusion method [AID1105919, Type: other]
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10
[SID104248738]
Cytotoxicity against LPS-stimulated mouse RAW264.7 cells assessed as cell viability at 50 uM after 24 hrs by MTT assay [AID736896, Type: Literature]
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11
[SID104248738]
IC50 Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 50 uM after 24 hrs by MTT assay [AID736897, Type: Literature]
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12
[SID104248738]
Antibacterial activity against Pseudomonas aeruginosa MTCC 2642 assessed as growth inhibition at 2 mg/mL after 24 hr by disk diffusion method [AID1105915, Type: other]
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13
[SID104248738]
Antibacterial activity against Escherichia coli MTCC 82 assessed as growth inhibition at 2 mg/mL after 24 hr by disk diffusion method [AID1105917, Type: other]
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14
[SID104248738]
IC50 Inhibition of ATP sythesis in freshly lysed Spinacia oleracea (spinach) chloroplasts [AID1090673, Type: Literature]
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15
[SID104248738]
Antibacterial activity against Bacillus subtilis MTCC 2451 assessed as growth inhibition at 2 mg/mL after 24 hr by disk diffusion method [AID1105921, Type: other]
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16
[SID104248738]
Antifungal activity against Candida albicans MTCC 3018 assessed as growth inhibition at 2 mg/mL after 48 hr by disk diffusion method [AID1105922, Type: other]
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17
[SID104248738]
Antifungal activity against Cryptococcus gastricus MTCC 1715 assessed as growth inhibition at 2 mg/mL after 48 hr by disk diffusion method [AID1105908, Type: other]
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18
[SID104248738]
Antifungal activity against Saccharomyces cerevisiae MTCC 172 assessed as growth inhibition at 2 mg/mL after 48 hr by disk diffusion method [AID1105911, Type: other]
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19
[SID104248738]
Antibacterial activity against Salmonella enterica subsp. enterica serovar Typhi MTCC 1251 assessed as growth inhibition at 2 mg/mL after 24 hr by disk diffusion method [AID1105912, Type: other]
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20
[SID104248738]
Antibacterial activity against Escherichia coli K-12 by microtiter plate assay [AID592503, Type: Literature]
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