Bookmark and Share
maleic acid (CID 444266) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(14)
 
 
Inactive(846)
 
 
Inconclusive(16)
 
 
Unspecified(4)
 
 
Top Targets:
NR LBD PPAR(29)
 
 
 
NR LBD AR(23)
 
 
 
NR LBD ER(23)
 
 
7TM GPCR Srx(19)
 
 
7TM GPCR Srsx(17)
 
 
BioAssay Types:
Confirmatory(450)
 
 
 
 
 
Screening(313)
 
 
Summary(72)
 
 
 
Literature(29)
 
 
 
 
BioActivity Types:
Potency(456)
 
 
 
 
 
IC50(11)
 
 
Kd(8)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 642    Data Row: 880   Total Pages: 44   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID57268340]
Potency 89.1251qHTS Assay for Inhibitors of JMJD2A-Tudor Domain [AID504339, Type: confirmatory]Chain A, Jmjd2a Tandem Tudor Domains In Complex With A Trimethylated Histone H4-K20 Peptide [gi:162330054]
View
2
[SID46391428]
Kd 440Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Aspartate Aminotransferase Hexamutant [gi:1127182]
View
3
[SID46391428]
Kd 440Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Aspartate Aminotransferase Hexamutant [gi:1127182]
View
4
[SID46391428]
Kd 440Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain B, Aspartate Aminotransferase Hexamutant [gi:1127183]
View
5
[SID46391428]
Kd 440Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain B, Aspartate Aminotransferase Hexamutant [gi:1127183]
View
6
[SID46393252]
Kd 3400Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Maleic Acid-bound Structure Of Srhept Mutant Of E. Coli Aspartate Aminotransferase [gi:55669978]
View
7
[SID46393252]
Kd 3400Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Maleic Acid-bound Structure Of Srhept Mutant Of E. Coli Aspartate Aminotransferase [gi:55669978]
View
8
[SID46393252]
Kd 3400Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain B, Maleic Acid-bound Structure Of Srhept Mutant Of E. Coli Aspartate Aminotransferase [gi:55669979]
View
9
[SID46393252]
Kd 3400Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain B, Maleic Acid-bound Structure Of Srhept Mutant Of E. Coli Aspartate Aminotransferase [gi:55669979]
View
10
[SID103681719]
Inhibition of wild type human recombinant mitochondrial NADP-ME expressed in Escherichia coli BL21 assessed as residual enzyme activity by spectrophotometry in absence of fumarate [AID429166, Type: Literature]NADP-dependent malic enzyme, mitochondrial [gi:215274021]
View
11
[SID46391428]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Aspartate Aminotransferase Hexamutant [gi:1127182]
View
12
[SID103681719]
Inhibition of human mitochondrial NADP-ME E59L mutant expressed in Escherichia coli XL-1 assessed as residual enzyme activity by spectrophotometry in presence of fumarate [AID429164, Type: Literature]
View
13
[SID103681719]
Inhibition of human mitochondrial NADP-ME E59L mutant expressed in Escherichia coli XL-1 assessed as residual enzyme activity by spectrophotometry in absence of fumarate [AID429165, Type: Literature]
View
14
[SID46393252]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Maleic Acid-bound Structure Of Srhept Mutant Of E. Coli Aspartate Aminotransferase [gi:55669978]
View
15
[SID103681719]
Literature-mined public compounds from Greene et al multi-species hepatotoxicity modelling dataset [AID588209, Type: Literature]
View
16
[SID103681719]
Human drug-induced liver injury (DILI) modelling dataset from Ekins et al [AID588210, Type: Literature]
View
17
[SID17389671]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
18
[SID57268340]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
19
[SID57268340]
Potency 1.122A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
View
20
[SID57268340]
Potency 1.636A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
View