Bookmark and Share
Acarbose (CID 444254) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(72)
 
 
Inactive(90)
 
 
Inconclusive(9)
 
 
Unspecified(1521)
 
 
Top Targets:
GH31 MGAM SI..(42)
 
 
 
7TM GPCR Srsx(17)
 
 
 
7TM GPCR Srx(16)
 
 
p450(10)
 
 
 
NR LBD ER(9)
 
 
 
 
BioAssay Types:
Literature(210)
 
 
 
 
 
Confirmatory(188)
 
 
 
 
 
Summary(24)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
IC50(199)
 
 
 
 
 
Potency(86)
 
 
 
 
Ki(11)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1689    Data Row: 1692   Total Pages: 85   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID46391424]
Ki 1e-06Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Refined Structure For The Complex Of Acarbose With Glucoamylase From Aspergillus Awamori Var. X100 To 2.4 Angstroms Resolution [gi:157829865]
View
2
[SID46391424]
Ki 1e-06Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Refined Structure For The Complex Of Acarbose With Glucoamylase From Aspergillus Awamori Var. X100 To 2.4 Angstroms Resolution [gi:157829865]
View
3
[SID103585278]
Ki 0.009Inhibition of mouse his-tagged ctMGAM-N2 expressed in Sf9 cells assessed as amount of glucose produced using maltose as a substrate after 45 mins by glucose oxidase assay [AID620760, Type: Literature]
View
4
[SID103585278]
Ki 0.028Inhibition of mouse his-tagged ctMGAM-N20 expressed in Sf9 cells assessed as amount of glucose produced using maltose as a substrate after 45 mins by glucose oxidase assay [AID620761, Type: Literature]
View
5
[SID103585278]
IC50 0.033Inhibition of Bacillus stearothermophilus alpha-glucosidase type IV [AID427710, Type: Literature]
View
6
[SID103585278]
IC50 0.034Inhibition of Bacillus stearothermophilus alpha-glucosidase type 4 [AID692014, Type: Literature]
View
7
[SID103585278]
IC50 0.049Inhibition of Bacillus stearothermophilus alpha glucosidase-4 [AID497106, Type: Literature]
View
8
[SID103585278]
IC50 0.1Inhibition of Bacillus stearothermophilus alpha-glucosidase [AID391607, Type: Literature]
View
9
[SID103585278]
IC50 0.1Inhibition of Saccharomyces cerevisiae alpha-glucosidase [AID391608, Type: Literature]
View
10
[SID103585278]
IC50 0.16Inhibition of Wistar rat small intestine maltase after 30 mins [AID550393, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
View
11
[SID103585278]
IC50 0.18Inhibition of rat intestinal maltase using moltose as substrate [AID711104, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
View
12
[SID103585278]
Ki 0.246Inhibition of mouse his-tagged ctSI expressed in Sf9 cells assessed as amount of glucose produced using maltose as a substrate after 45 mins by glucose oxidase assay [AID620763, Type: Literature]
View
13
[SID103585278]
Ki 0.34Competitive inhibition of Bacillus stearothermophilus alpha-glucosidase assessed as production of chromogenic p-Nitrphenol measured after 3 mins by HPLC and Michaelis-Menten equation [AID590733, Type: Literature]Exo-alpha-1,4-glucosidase [gi:75499522]
View
14
[SID103585278]
IC50 0.35Inhibition of rat intestinal brush border membrane maltase [AID342793, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
View
15
[SID103585278]
IC50 0.4Inhibition of rat intestinal sucrase using sucrose as substrate assessed as D-glucose release from substrate preincubated for 15 mins measured after 60 mins [AID763817, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
View
16
[SID103585278]
IC50 0.54Inhibition of rat intestinal alpha-glucosidase using sucrose as substrate assessed as glucose formation incubated for 10 mins prior to substrate addition measured after 30 mins by glucose oxidase method [AID778972, Type: Literature]
View
17
[SID103585278]
IC50 0.56Inhibition of rat intestinal brush border membrane sucrase [AID342797, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
View
18
[SID103585278]
IC50 0.996Inhibition of human salivary alpha-amylase [AID404692, Type: Literature]Alpha-amylase 1 [gi:1351933]
View
19
[SID103585278]
IC50 1.5Inhibition of rat small intestinal sucrase after 30 mins by glucose-oxidase method [AID594100, Type: Literature]Sucrase-isomaltase, intestinal [gi:1351132]
View
20
[SID103585278]
IC50 1.5Inhibition of rat intestinal alpha-glucosidase maltase using maltose as substrate preincubated for 10 mins prior substrate addition measured after 40 mins by spectrophotometry [AID647236, Type: Literature]Lysosomal alpha-glucosidase [gi:81885339]
View